TcYC6_0012480

Elongation factor G 2, mitochondrial, putative
Trypanosoma cruzi Y C6 OG6: OG6_103657 OG7: OG7_0003018 150 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 150 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0175540 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcYC6_0062450 ⚠
putative choline/ethanolamine kinase
— OG7
TcYC6_0108610 ⚠
U-box domain protein, putative
— OG7
TcYC6_0054200 ⚠
6-phosphogluconolactonase, putative
— OG7
TcYC6_0008340 ⚠
phosphoenolpyruvate mutase, putative
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0019440 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— OG7
TcYC6_0054750 ⚠
dihydroorotase, putative
— OG7
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0065780 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0123690 ⚠
Component of motile flagella 12
— OG7
TcYC6_0055760 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcYC6_0064790 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcYC6_0064930 ⚠
hypothetical protein
— OG7
TcYC6_0064940 ⚠
putative GMP synthase
— OG7
TcYC6_0094890 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG7
TcYC6_0115350 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— OG7
TcYC6_0095870 ⚠
adenosine kinase, putative
— OG7
TcYC6_0123640 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcYC6_0012390 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
TcYC6_0095860 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcYC6_0059630 ⚠
thimet oligopeptidase, putative
— OG7
TcYC6_0042220 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcYC6_0090820 ⚠
adenosine kinase, putative
— OG7
TcYC6_0095910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0085920 ⚠
deoxyhypusine hydroxylase, putative
— OG7
TcYC6_0036070 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
TcYC6_0115920 ⚠
alcohol dehydrogenase, putative
— OG7
TcYC6_0068890 ⚠
cysteine desulfurase, putative
— OG7
TcYC6_0116190 ⚠
UTP-glucose-1-phosphate uridylyltransferase 2
— OG7
TcYC6_0055560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016600 ⚠
Mitochondrial Editosome-like Complex TUTase
— OG7
TcYC6_0119710 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0045140 ⚠
Component of motile flagella 15
— OG7
TcYC6_0072740 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— OG7
TcYC6_0115110 ⚠
pyruvate kinase 2, putative
— OG7
TcYC6_0111570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0051250 ⚠
terminal uridylyltransferase 4
— OG7
TcYC6_0022140 ⚠
RNA polymerase II, putative
— OG7
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.