TcYC6_0094890

2-hydroxy-3-oxopropionate reductase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101839 OG7: OG7_0002731 238 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 238 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— Both
TcYC6_0080630 ⚠
elongation factor 2
— OG7
TcYC6_0099160 ⚠
alpha-adaptin-like, putative
— OG7
TcYC6_0079830 ⚠
SNF1-related protein kinase, putative
— OG7
TcYC6_0006270 ⚠
Enoyl-CoA hydratase/isomerase family, putativ
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0044720 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcYC6_0021970 ⚠
mitochondrial RNA binding complex 1 subunit,
— OG7
TcYC6_0072730 ⚠
hypothetical protein
— OG7
TcYC6_0074090 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0075770 ⚠
aldo-keto reductase, putative
— OG7
TcYC6_0004150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0076430 ⚠
SSU ribosomal protein, mitochondrial, putativ
— OG7
TcYC6_0028940 ⚠
Mitochondrial SSU ribosomal protein, putative
— OG7
TcYC6_0001620 ⚠
Mitochondrial SSU ribosomal protein, putative
— OG7
TcYC6_0004030 ⚠
Mitochondrial SSU ribosomal protein, putative
— OG7
TcYC6_0024560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0069620 ⚠
Mitochondrial SSU ribosomal protein, putative
— OG7
TcYC6_0065300 ⚠
Mitochondrial ATP synthase subunit, putative
— OG7
TcYC6_0042420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0054260 ⚠
mitochondrial ribosomal protein L17
— OG7
TcYC6_0034760 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0003450 ⚠
Mitochondrial ATP synthase subunit, putative
— OG7
TcYC6_0097690 ⚠
LSU ribosomal protein, mitochondrial, putativ
— OG7
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0045150 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— Both
TcYC6_0091520 ⚠
hypothetical protein, conserved
— Both
TcYC6_0124360 ⚠
hypothetical protein, conserved
— Both
TcYC6_0046970 ⚠
proteasome activator protein pa26, putative
— Both
TcYC6_0122700 ⚠
hypothetical protein, conserved
— Both
TcYC6_0068400 ⚠
Importin 1
— Both
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— Both
TcYC6_0016510 ⚠
hypothetical protein, conserved
— Both
TcYC6_0054390 ⚠
Met-10+ like-protein, putative
— Both
TcYC6_0012390 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
TcYC6_0045140 ⚠
Component of motile flagella 15
— Both
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0103080 ⚠
Kinesin-13 5, putative
— OG7
TcYC6_0101740 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.