TcYC6_0074380

UBA/TS-N domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_129093 OG7: OG7_0004831 179 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 179 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0094890 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0054390 ⚠
Met-10+ like-protein, putative
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— Both
TcYC6_0100590 ⚠
hypothetical protein, conserved
— Both
TcYC6_0115110 ⚠
pyruvate kinase 2, putative
— Both
TcYC6_0062990
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0100460 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcYC6_0016600 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcYC6_0115350 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcYC6_0079840 ⚠
eukaryotic translation initiation factor 6 (e
— Both
TcYC6_0118110 ⚠
TAP42-like family, putative
— Both
TcYC6_0108610 ⚠
U-box domain protein, putative
— Both
TcYC6_0054200 ⚠
6-phosphogluconolactonase, putative
— Both
TcYC6_0008340 ⚠
phosphoenolpyruvate mutase, putative
— Both
TcYC6_0006560 ⚠
Protein of unknown function (DUF2009), putati
— Both
TcYC6_0118000 ⚠
NPL4 family, putative
— Both
TcYC6_0115180 ⚠
mevalonate-diphosphate decarboxylase, putativ
— Both
TcYC6_0019440 ⚠
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
TcYC6_0054750 ⚠
dihydroorotase, putative
— Both
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcYC6_0119740 ⚠
hypothetical protein, conserved
— Both
TcYC6_0075790 ⚠
TPR-repeat protein, putative
— OG6
TcYC6_0065780 ⚠
hypothetical protein, conserved
— Both
TcYC6_0080780 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcYC6_0052500 ⚠
protein phosphatase 2C
— OG6
TcYC6_0061710 ⚠
PITH domain-containing protein
— Both
TcYC6_0115010 ⚠
N-myristoyl transferase, putative
— Both
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0122400 ⚠
hypothetical protein, conserved
— Both
TcYC6_0107700 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0103080 ⚠
Kinesin-13 5, putative
— OG7
TcYC6_0072630 ⚠
diphthamide synthesis protein
— OG7
TcYC6_0115440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043290 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcYC6_0043280 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcYC6_0075770 ⚠
aldo-keto reductase, putative
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0102010 ⚠
CMGC/MAPK protein kinase, putative
— OG7
TcYC6_0018590 ⚠
glutathione synthetase, putative
— OG7
TcYC6_0009840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012100 ⚠
elongation factor G2-like protein, putative
— OG7
TcYC6_0110350 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
TcYC6_0078640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.