TcYC6_0006560

Protein of unknown function (DUF2009), putative
Trypanosoma cruzi Y C6 OG6: OG6_106962 OG7: OG7_0012088 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0152900 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0150680 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0121550 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0070400 ⚠
Protein of unknown function (DUF2009), putati
— Both
TcYC6_0054780 ⚠
transaldolase, putative
— Both
TcYC6_0051310 ⚠
hypothetical protein, conserved
— Both
TcYC6_0112520 ⚠
hypothetical protein, conserved
— Both
TcYC6_0112660 ⚠
CS domain containing protein, putative
— Both
TcYC6_0070940 ⚠
Co-chaperone protein P23
— Both
TcYC6_0102610 ⚠
Alpha/beta hydrolase family, putative
— Both
TcYC6_0097640 ⚠
RNA-binding protein, putative
— OG6
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— Both
TcYC6_0049770 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TcYC6_0053430 ⚠
Alpha/beta hydrolase family, putative
— Both
TcYC6_0096570 ⚠
epsilon-adaptin, putative
— Both
TcYC6_0091050 ⚠
phosphomannomutase-like protein, putative
— Both
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— Both
TcYC6_0110890 ⚠
Flagellum attachment zone protein 19, putativ
— Both
TcYC6_0012390 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
TcYC6_0084720 ⚠
rotamase, putative
— OG6
TcYC6_0051940 ⚠
hypothetical protein, conserved
— Both
TcYC6_0045140 ⚠
Component of motile flagella 15
— Both
TcYC6_0045150 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcYC6_0030300 ⚠
alanine racemase, putative
— Both
TcYC6_0092460 ⚠
SEP domain containing protein, putative
— Both
TcYC6_0074380 ⚠
UBA/TS-N domain containing protein, putative
— Both
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0107700 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0110350 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
TcYC6_0009840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009920 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcYC6_0022140 ⚠
RNA polymerase II, putative
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0012480 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0051250 ⚠
terminal uridylyltransferase 4
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0084730 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.