TcYC6_0125230

nicotinate phosphoribosyltransferase, putative
Trypanosoma cruzi Y C6 OG6: OG6_109462 OG7: OG7_0015320 180 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 180 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0076050 ⚠
esterase, putative
— Both
TcYC6_0007710
Biotin--acetyl-CoA-carboxylase ligase, putati
— Both
TcYC6_0063760
mitogen-activated protein kinase 3, putative
— OG6
TcYC6_0049100
Macro domain containing protein, putative
— Both
TcYC6_0075930 ⚠
protein phosphatase 2C, putative
— OG6
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— Both
TcYC6_0049770 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TcYC6_0115110
pyruvate kinase 2, putative
— Both
TcYC6_0175660 ⚠
monothiol glutaredoxin, putative
— Both
TcYC6_0073580 ⚠
Serine-threonine kinase receptor-associated p
— Both
TcYC6_0009250 ⚠
hypothetical protein, conserved
— Both
TcYC6_0062990
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0100460 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcYC6_0016600 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcYC6_0115350
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
TcYC6_0079840
eukaryotic translation initiation factor 6 (e
— Both
TcYC6_0118110
TAP42-like family, putative
— Both
TcYC6_0065990 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TcYC6_0108610
U-box domain protein, putative
— Both
TcYC6_0054200
6-phosphogluconolactonase, putative
— Both
TcYC6_0008340
phosphoenolpyruvate mutase, putative
— Both
TcYC6_0006560 ⚠
Protein of unknown function (DUF2009), putati
— Both
TcYC6_0118000
NPL4 family, putative
— Both
TcYC6_0115180
mevalonate-diphosphate decarboxylase, putativ
— Both
TcYC6_0115440 ⚠
hypothetical protein, conserved
— Both
TcYC6_0019440
Bifunctional NAD(P)H-hydrate repair enzyme
— Both
TcYC6_0054750 ⚠
dihydroorotase, putative
— Both
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— Both
TcYC6_0119740
hypothetical protein, conserved
— Both
TcYC6_0075790 ⚠
TPR-repeat protein, putative
— OG6
TcYC6_0032120 ⚠
hypothetical protein, conserved
— Both
TcYC6_0052370 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0065780
hypothetical protein, conserved
— Both
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— Both
TcYC6_0094070 ⚠
dephospho-CoA kinase, putative
— OG6
TcYC6_0080780 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcYC6_0050990 ⚠
superoxide dismutase, putative
— Both
TcYC6_0050860 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0052500 ⚠
protein phosphatase 2C
— OG6
TcYC6_0061710
PITH domain-containing protein
— Both
TcYC6_0115010
N-myristoyl transferase, putative
— Both
TcYC6_0009260 ⚠
hypothetical protein, conserved
— Both
TcYC6_0044570
hypothetical protein, conserved
— Both
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0030460
Ran-binding protein
— Both
TcYC6_0011810 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcYC6_0085450 ⚠
monothiol glutaredoxin, putative
— OG7
TcYC6_0095240 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcYC6_0009840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009920 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.