TcYC6_0073580

Serine-threonine kinase receptor-associated protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_103369 OG7: OG7_0003947 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0012150 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0080540 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0049070 ⚠
translation initiation factor
— OG7
TcYC6_0098360 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0121120 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0047610 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0094820 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0051680 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0070700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0076500 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0050280 ⚠
hypothetical protein
— OG7
TcYC6_0117590 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0082200 ⚠
Eukaryotic translation initiation factor 1, p
— OG7
TcYC6_0067090 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
TcYC6_0076180 ⚠
esterase, putative
— Both
TcYC6_0076050 ⚠
esterase, putative
— Both
TcYC6_0044570 ⚠
hypothetical protein, conserved
— Both
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TcYC6_0112320 ⚠
Soluble NSF attachment protein, SNAP, putativ
— Both
TcYC6_0122380 ⚠
Sucrase/ferredoxin-like, putative
— Both
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— OG7
TcYC6_0030620 ⚠
chaperonin/T-complex protein 1 gamma subunit,
— OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcYC6_0023210 ⚠
T-complex protein 1, delta subunit, putative
— OG7
TcYC6_0053320 ⚠
chaperonin containing t-complex protein, puta
— OG7
TcYC6_0050130 ⚠
chaperonin alpha subunit, putative
— OG7
TcYC6_0121250 ⚠
T-complex protein 1, theta subunit, putative
— OG7
TcYC6_0072350 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119230 ⚠
Eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0113410 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
TcYC6_0085450 ⚠
monothiol glutaredoxin, putative
— OG7
TcYC6_0051940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016060 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
TcYC6_0049100 ⚠
Macro domain containing protein, putative
— Both
TcYC6_0052370 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0032120 ⚠
hypothetical protein, conserved
— Both
TcYC6_0115440 ⚠
hypothetical protein, conserved
— Both
TcYC6_0065990 ⚠
iron superoxide dismutase A, mitochondrial
— Both
TcYC6_0064180 ⚠
basal body component, putative
— Both
TcYC6_0062990
Mitogen-activated protein kinase 10, putative
— OG6
TcYC6_0009250 ⚠
hypothetical protein, conserved
— Both
TcYC6_0175660 ⚠
monothiol glutaredoxin, putative
— Both
TcYC6_0094070 ⚠
dephospho-CoA kinase, putative
— OG6
TcYC6_0063760
mitogen-activated protein kinase 3, putative
— OG6
TcYC6_0062220 ⚠
thioredoxin-like protein, putative
— Both
TcYC6_0098760 ⚠
PAS-domain containing phosphoglycerate kinase
— Both
TcYC6_0016050 ⚠
phosphoglycerate kinase, putative
— Both
TcYC6_0031740 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.