TcYC6_0098360

eukaryotic translation initiation factor 3 subunit d
Trypanosoma cruzi Y C6 OG6: OG6_102252 OG7: OG7_0006808 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0049070
translation initiation factor
— +2 more Both
TcYC6_0073580 ⚠
Serine-threonine kinase receptor-associated p
— OG7
TcYC6_0089850
eukaryotic translation initiation factor 3 su
— OG6
TcYC6_0012150
Eukaryotic translation initiation factor 3 su
— Both
TcYC6_0121120
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0080540
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0007260 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0028610
hypothetical protein, conserved
— OG7
TcYC6_0119230
Eukaryotic translation initiation factor 3 su
— Both
TcYC6_0126490 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
TcYC6_0099660 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0114670 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcYC6_0066250 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0062920 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0086600
hypothetical protein
— Both
TcYC6_0014480 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcYC6_0109440
hypothetical protein, conserved
— Both
TcYC6_0007150 ⚠
60S ribosomal protein L10a, putative
— Both
TcYC6_0115810 ⚠
60S ribosomal protein L10a, putative
— Both
TcYC6_0114250
RNA-binding protein, putative
— OG7
TcYC6_0075410
repressor activator protein 1
— OG7
TcYC6_0102040
hypothetical protein, conserved
— OG7
TcYC6_0093810
hypothetical protein, conserved
— OG7
TcYC6_0070750 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcYC6_0046860
hypothetical protein, conserved
— OG7
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0028450 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcYC6_0089660 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
TcYC6_0099230 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0053190
hypothetical protein, conserved
— OG7
TcYC6_0098600 ⚠
glutamyl-tRNA synthetase, putative
— Both
TcYC6_0116600 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
TcYC6_0011710
Coatomer subunit gamma
— Both
TcYC6_0095380
spliceosome-associated protein, putative
— Both
TcYC6_0047610
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0092980
Tripartite attachment complex protein 102
— Both
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— Both
TcYC6_0050700
CS domain/TPR repeat, putative
— Both
TcYC6_0051680
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0125570 ⚠
translation elongation factor 1-beta, putativ
— Both
TcYC6_0087400 ⚠
25 kDa translation elongation factor 1-beta,
— Both
TcYC6_0098390
putative kinesin
— OG6
TcYC6_0069180 ⚠
ATP-dependent RNA helicase, putative
— Both
TcYC6_0031280
hypothetical protein, conserved
— Both
TcYC6_0082200
Eukaryotic translation initiation factor 1, p
— Both
TcYC6_0074230 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
TcYC6_0109730
hypothetical protein, conserved
— Both
TcYC6_0025170 ⚠
60S ribosomal protein L10, putative
— Both
TcYC6_0100420
splicing factor TSR1, putative
— Both
TcYC6_0112490
eukaryotic translation initiation factor 5, p
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.