TcYC6_0114670

ATP-dependent RNA helicase HEL67
Trypanosoma cruzi Y C6 OG6: OG6_100461 OG7: OG7_0000120 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0021560 ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
TcYC6_0096210 ⚠
small nuclear ribonucleoprotein Sm-E, putativ
— OG7
TcYC6_0070930 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— Both
TcYC6_0005360 ⚠
amidohydrolase, putative
— OG7
TcYC6_0036970 ⚠
ribonucleoside-diphosphate reductase small ch
— OG7
TcYC6_0079690 ⚠
RNA editing complex protein MP61, putative
— OG7
TcYC6_0072200 ⚠
RNA editing complex protein MP46, putative
— OG7
TcYC6_0005350 ⚠
aminoacylase, putative
— OG7
TcYC6_0005340 ⚠
amidohydrolase, putative
— OG7
TcYC6_0034870 ⚠
zinc finger (CCCH type) protein, putative
— OG7
TcYC6_0037230 ⚠
translation-associated element 2, putative
— OG7
TcYC6_0080040 ⚠
MP24, putative
— OG7
TcYC6_0121230 ⚠
RNA editing complex protein MP63, putative
— OG7
TcYC6_0095380 ⚠
spliceosome-associated protein, putative
— OG7
TcYC6_0067410 ⚠
U3 small nucleolar RNA-associated protein 6,
— OG7
TcYC6_0072130 ⚠
hypothetical protein
— OG7
TcYC6_0117290 ⚠
zinc finger protein 3
— OG7
TcYC6_0098940 ⚠
zinc finger-domain protein
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0074230 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— OG7
TcYC6_0006450 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— OG7
TcYC6_0109730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0063100 ⚠
putative protein transport protein SEC23
— OG7
TcYC6_0049070 ⚠
translation initiation factor
— OG7
TcYC6_0100420 ⚠
splicing factor TSR1, putative
— OG7
TcYC6_0115810 ⚠
60S ribosomal protein L10a, putative
— OG7
TcYC6_0079440 ⚠
N-acetyltransferase subunit Nat1, putative
— OG7
TcYC6_0072590 ⚠
Nucleoporin NUP59
— OG7
TcYC6_0007150 ⚠
60S ribosomal protein L10a, putative
— OG7
TcYC6_0114250 ⚠
RNA-binding protein, putative
— OG7
TcYC6_0057940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053860 ⚠
Outer row dynein-assembly protein 7
— OG7
TcYC6_0005570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0018540 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
TcYC6_0003450 ⚠
Mitochondrial ATP synthase subunit, putative
— Both
TcYC6_0077990 ⚠
small nuclear ribonucleoprotein SmD2, putativ
— Both
TcYC6_0077770 ⚠
small nuclear ribonucleoprotein SmD2, putativ
— Both
TcYC6_0093620 ⚠
small nuclear ribonucleoprotein, putative
— Both
TcYC6_0076330 ⚠
small nuclear ribonucleoprotein protein, puta
— Both
TcYC6_0011240 ⚠
U5 snRNP-specific 40 kDa protein, putative
— Both
TcYC6_0065300 ⚠
Mitochondrial ATP synthase subunit, putative
— Both
TcYC6_0093050 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0111700 ⚠
mitochondrial protein 99, putative
— OG7
TcYC6_0059020 ⚠
RNA-editing complex protein MP100, putative
— OG7
TcYC6_0016750 ⚠
RNA-editing nuclease 1
— OG7
TcYC6_0057340 ⚠
Cupin-like domain containing protein, putativ
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.