TcYC6_0036970

ribonucleoside-diphosphate reductase small chain, putative
Trypanosoma cruzi Y C6 OG6: OG6_100537 OG7: OG7_0003661 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0067410
U3 small nucleolar RNA-associated protein 6,
— Both
TcYC6_0005570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053860 ⚠
Outer row dynein-assembly protein 7
— OG7
TcYC6_0071260 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0016660
conserved protein, unknown function
— Both
TcYC6_0034920 ⚠
ATP-dependent protease ATPase subunit HslU1,
— Both
TcYC6_0121550
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0117610
hypothetical protein, conserved
— OG6
TcYC6_0088430
EAP30/Vps36 family, putative
— Both
TcYC6_0057340
Cupin-like domain containing protein, putativ
— Both
TcYC6_0075310 ⚠
hypothetical protein
— Both
TcYC6_0107920
tryptophanyl-tRNA synthetase, putative
— OG6
TcYC6_0076330
small nuclear ribonucleoprotein protein, puta
— Both
TcYC6_0070390
elongation factor 1-alpha (ef-1-alpha), putat
— OG6
TcYC6_0014480 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— Both
TcYC6_0123050
adenylyl cyclase-associated protein, putative
— Both
TcYC6_0175230 ⚠
regulator of chromosome condensation 1-like p
— OG7
TcYC6_0120330 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0031400 ⚠
trypanothione synthetase, putative
— OG7
TcYC6_0077370 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0028450 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
TcYC6_0077360 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0120660 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0069180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0080560 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0113550 ⚠
FKBP-type peptidylprolyl cis-trans isomerase,
— OG7
TcYC6_0057750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0084700
endo-beta-N-acetylglucosaminidase, putative
— Both
TcYC6_0099660 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0062920 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0066250 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0056280 ⚠
putative regulator of chromosome condensation
— OG7
TcYC6_0114670 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcYC6_0126490 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
TcYC6_0047800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0089210 ⚠
hypothetical protein
— OG7
TcYC6_0113560 ⚠
macrophage infectivity potentiator, precursor
— OG7
TcYC6_0093050
hypothetical protein, conserved
— Both
TcYC6_0096260
pyridoxal kinase, putative
— Both
TcYC6_0098600 ⚠
glutamyl-tRNA synthetase, putative
— Both
TcYC6_0076460 ⚠
trypanothione synthetase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.