TcYC6_0121770

protein transport protein SEC23
Trypanosoma cruzi Y C6 OG6: OG6_100992 OG7: OG7_0004996 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0061220 ⚠
helicase, putative
— OG7
TcYC6_0066250 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0062920 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0014480 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0012520 ⚠
p21-C-terminal region-binding protein, putati
— OG7
TcYC6_0106440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcYC6_0059600 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0099660 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0043350 ⚠
zinc finger ccch and cchc domain-containing p
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0095240 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcYC6_0011810 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcYC6_0095730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012030 ⚠
hypothetical protein
— OG7
TcYC6_0061260 ⚠
helicase, putative
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— OG7
TcYC6_0077260 ⚠
translation initiation factor IF-2, putative
— OG7
TcYC6_0101260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115840 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcYC6_0061280 ⚠
helicase, putative
— OG7
TcYC6_0009310 ⚠
Ubiquitin family, putative
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0110770 ⚠
aspartyl aminopeptidase, putative
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0072080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0057340 ⚠
Cupin-like domain containing protein, putativ
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0060680 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0111640 ⚠
putative ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0119320 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0100560 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcYC6_0068590 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0045680 ⚠
TLD, putative
— OG7
TcYC6_0040110 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0045770 ⚠
hypothetical protein
— OG7
TcYC6_0072740 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— OG7
TcYC6_0065870 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.