TcYC6_0061280

helicase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100332 OG7: OG7_0003299 174 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 174 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— +2 more Both
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0062380 ⚠
threonyl-tRNA synthetase, putative
— Both
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— Both
TcYC6_0072920 ⚠
phenylalanyl-tRNA synthetase (beta subunit),
— Both
TcYC6_0065870 ⚠
hypothetical protein, conserved
— Both
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0095370 ⚠
hypothetical protein, conserved
— Both
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— Both
TcYC6_0116560 ⚠
prolyl-tRNA synthetase, putative
— +2 more Both
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0081730 ⚠
putative synaptojanin
— OG7
TcYC6_0072610 ⚠
heat shock protein 84, putative
— OG7
TcYC6_0108590 ⚠
heat shock protein 90, putative
— OG7
TcYC6_0079620 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcYC6_0070640 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcYC6_0088260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0085910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0040110 ⚠
hypothetical protein, conserved
— Both
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0090640 ⚠
ruvB-like DNA helicase, putative
— Both
TcYC6_0095730 ⚠
hypothetical protein, conserved
— Both
TcYC6_0050640 ⚠
ubiquitin hydrolase, putative
— Both
TcYC6_0045070 ⚠
hypothetical protein
— Both
TcYC6_0043350 ⚠
zinc finger ccch and cchc domain-containing p
— Both
TcYC6_0034770 ⚠
ribonucleoprotein p18, mitochondrial precurso
— Both
TcYC6_0043360 ⚠
PUB domain containing protein, putative
— Both
TcYC6_0084300 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
TcYC6_0083540 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
TcYC6_0114860 ⚠
Histone chaperone Rttp106-like, putative
— Both
TcYC6_0046920 ⚠
vacuolar ATP synthase subunit d
— Both
TcYC6_0028450 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0109610 ⚠
carnitine/choline acetyltransferase, putative
— OG7
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0007230 ⚠
glycyl-tRNA synthetase, putative
— Both
TcYC6_0123380 ⚠
hypothetical protein, conserved
— Both
TcYC6_0120270 ⚠
putative Leucine rich repeat
— Both
TcYC6_0064660 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.