TcYC6_0046920

vacuolar ATP synthase subunit d
Trypanosoma cruzi Y C6 OG6: OG6_101069 OG7: OG7_0005997 121 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 121 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0022120
ATP synthase F1 subunit gamma protein, putati
— Both
TcYC6_0095370
hypothetical protein, conserved
— Both
TcYC6_0061240 ⚠
hypothetical protein, conserved
— Both
TcYC6_0066100 ⚠
ubiquitin-activating enzyme
— Both
TcYC6_0069500
hypothetical protein, conserved
— Both
TcYC6_0073420
hypothetical protein, conserved
— Both
TcYC6_0107880
Facilitates chromatin transcription complex s
— Both
TcYC6_0024850 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0062380
threonyl-tRNA synthetase, putative
— Both
TcYC6_0124540 ⚠
heat shock protein 85, putative
— +2 more Both
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcYC6_0065870
hypothetical protein, conserved
— Both
TcYC6_0062940
hypothetical protein, conserved
— Both
TcYC6_0088920
Zeta toxin, putative
— Both
TcYC6_0032520
GDP-mannose pyrophosphorylase
— Both
TcYC6_0061260 ⚠
helicase, putative
— Both
TcYC6_0015540
dihydrolipoamide branched chain transacylase,
— Both
TcYC6_0061280 ⚠
helicase, putative
— Both
TcYC6_0124550 ⚠
putative heat shock protein 85
— +2 more Both
TcYC6_0026330 ⚠
calpain-like cysteine peptidase
— OG6
TcYC6_0061220 ⚠
helicase, putative
— Both
TcYC6_0026340 ⚠
hypothetical protein
— OG6
TcYC6_0017040 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0031670
pteridine reductase
— Both
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— Both
TcYC6_0120590 ⚠
putative Leucine rich repeat
— Both
TcYC6_0114860
Histone chaperone Rttp106-like, putative
— Both
TcYC6_0120270 ⚠
putative Leucine rich repeat
— Both
TcYC6_0123380
hypothetical protein, conserved
— Both
TcYC6_0009670
hexokinase, putative
— Both
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0005960 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0073500 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcYC6_0068480 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0084200 ⚠
ubiquitin activating enzyme, putative
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0028200 ⚠
putative inositol/phosphatidylinositol phosph
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0081730 ⚠
putative synaptojanin
— OG7
TcYC6_0072610 ⚠
heat shock protein 84, putative
— OG7
TcYC6_0108590 ⚠
heat shock protein 90, putative
— OG7
TcYC6_0079620 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.