TcYC6_0005960

Adaptor protein complex AP-3 subunit beta-3
Trypanosoma cruzi Y C6 OG6: OG6_101595 OG7: OG7_0001921 219 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 219 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG7
TcYC6_0034770 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
TcYC6_0083110 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0043840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— OG7
TcYC6_0059570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0030660 ⚠
coronin, putative
— OG7
TcYC6_0084300 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcYC6_0125480 ⚠
adenylate kinase, putative
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0053470 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0127470 ⚠
cullin-like protein, putative
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0108120 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcYC6_0044050 ⚠
tubulin-tyrosine ligase-like protein
— OG7
TcYC6_0016680 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0091590 ⚠
hypothetical protein
— OG7
TcYC6_0083540 ⚠
WD domain, G-beta repeat/PFU (PLAA family ubi
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0055440 ⚠
cullin 3, putative
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0126910 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.