TcYC6_0124130

structural maintenance of chromosome (SMC), putative
Trypanosoma cruzi Y C6 OG6: OG6_101492 OG7: OG7_0001761 200 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 200 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0089320 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0066360 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcYC6_0116010 ⚠
periodic tryptophan protein 2, putative
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0053870 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124520 ⚠
CMGC family protein kinase, putative
— OG7
TcYC6_0117990 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0046170 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcYC6_0063860 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088400 ⚠
hypothetical protein
— OG7
TcYC6_0095570 ⚠
CDC16, putative
— OG7
TcYC6_0090600 ⚠
ZFP family member, putative
— OG7
TcYC6_0125360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0065500 ⚠
histone deacetylase, putative
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0103930 ⚠
acetyl-CoA carboxylase
— OG7
TcYC6_0089950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0094210 ⚠
ccr4-not transcription complex subunit
— OG7
TcYC6_0052960 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0106680 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0126610 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
TcYC6_0108000 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
TcYC6_0059570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0065860 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0063980 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0075060 ⚠
RNA polymerase I second largest subunit
— OG7
TcYC6_0050970 ⚠
hypothetical protein
— OG7
TcYC6_0083610 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021590 ⚠
adenylate kinase, putative
— OG7
TcYC6_0043480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0011590 ⚠
gamma-tubulin complex subunit
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0051300 ⚠
histone deacetylase, putative
— OG7
TcYC6_0096290 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
TcYC6_0021890 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0018790 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0032440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0005960 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcYC6_0095490 ⚠
pdz domain containing protein, putative
— OG7
TcYC6_0097460 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.