TcYC6_0089320

Glycosyl hydrolase family 65 central catalytic domain/Haloacid dehalogenase-like hydrolase, putative
Trypanosoma cruzi Y C6 OG6: OG6_143485 OG7: OG7_0042752 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0106680
hypothetical protein, conserved
— Both
TcYC6_0116000
hypothetical protein, conserved
— +2 more Both
TcYC6_0007640
glycosyl hydrolase, putative
— Both
TcYC6_0098850 ⚠
casein kinase 1 isoform 2
— OG7
TcYC6_0005490 ⚠
cell division cycle protein, putative
— OG7
TcYC6_0067060 ⚠
peroxisome assembly protein, putative
— OG7
TcYC6_0074050 ⚠
vesicular transport protein (CDC48-like), put
— OG7
TcYC6_0097540 ⚠
AAA ATPase
— OG7
TcYC6_0113630 ⚠
ABC transport system ATP-binding protein, put
— OG7
TcYC6_0074710 ⚠
ATPase
— OG7
TcYC6_0121420 ⚠
beta adaptin, putative
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0107680 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcYC6_0015950 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcYC6_0028610
hypothetical protein, conserved
— OG7
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0064200
hypothetical protein, conserved
— OG7
TcYC6_0090170 ⚠
casein kinase, putative
— OG7
TcYC6_0119200 ⚠
casein kinase I, putative
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0128020 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0046170 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0083110 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0059570
hypothetical protein, conserved
— OG7
TcYC6_0125480 ⚠
adenylate kinase, putative
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0106160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0127470 ⚠
cullin-like protein, putative
— OG7
TcYC6_0026690 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
TcYC6_0126910 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.