TcYC6_0121420

beta adaptin, putative
Trypanosoma cruzi Y C6 OG6: OG6_100684 OG7: OG7_0001921 222 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 222 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— Both
TcYC6_0050240 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
TcYC6_0042450 ⚠
Mono-functional DNA-alkylating methyl methane
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0059570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0125360 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0066450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044080 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0066240 ⚠
delta-adaptin
— OG7
TcYC6_0121870 ⚠
Cell division control protein 48, putative
— OG7
TcYC6_0031280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0067110 ⚠
adenylate kinase, putative
— OG7
TcYC6_0021590 ⚠
adenylate kinase, putative
— OG7
TcYC6_0125480 ⚠
adenylate kinase, putative
— OG7
TcYC6_0116010 ⚠
periodic tryptophan protein 2, putative
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0048640 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0101400 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0055570 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcYC6_0083740 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0005640 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016680 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0006110 ⚠
PQQ-like domain/WD domain, G-beta repeat/Utp2
— OG7
TcYC6_0064200 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044190 ⚠
Phosphoenolpyruvate carboxykinase, related
— OG7
TcYC6_0094210 ⚠
ccr4-not transcription complex subunit
— OG7
TcYC6_0097300 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcYC6_0066660 ⚠
hypothetical protein
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0066650 ⚠
putative tubulin tyrosine ligase
— OG7
TcYC6_0054430 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0108120 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcYC6_0044050 ⚠
tubulin-tyrosine ligase-like protein
— OG7
TcYC6_0106160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
TcYC6_0117990 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0126910 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcYC6_0026690 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0084010 ⚠
putative cullin
— OG7
TcYC6_0055440 ⚠
cullin 3, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.