TcYC6_0018790

WD domain, G-beta repeat/Dip2/Utp12 Family, putative
Trypanosoma cruzi Y C6 OG6: OG6_102330 OG7: OG7_0007230 134 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 134 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0116010
periodic tryptophan protein 2, putative
— Both
TcYC6_0006110
PQQ-like domain/WD domain, G-beta repeat/Utp2
— Both
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0017410
STE group serine/threonine-protein kinase, pu
— OG6
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcYC6_0065270 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0123300 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0072160 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0003610 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcYC6_0064200
hypothetical protein, conserved
— OG7
TcYC6_0030470 ⚠
putative DNA polymerase theta (helicase domai
— OG7
TcYC6_0052820 ⚠
RNA helicase
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0121420 ⚠
beta adaptin, putative
— OG7
TcYC6_0083110 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0080110 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0127470 ⚠
cullin-like protein, putative
— OG7
TcYC6_0026690 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0025330 ⚠
UMP/CMP kinase, putative
— OG7
TcYC6_0125480 ⚠
adenylate kinase, putative
— OG7
TcYC6_0059570
hypothetical protein, conserved
— OG7
TcYC6_0097300 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0018310 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0044540 ⚠
neurobeachin/beige-like protein
— OG7
TcYC6_0037160 ⚠
polyubiquitin
— OG7
TcYC6_0037170 ⚠
polyubiquitin
— OG7
TcYC6_0012300 ⚠
cullin 2, putative
— OG7
TcYC6_0071440 ⚠
DNA replication licensing factor MCM9, putati
— OG7
TcYC6_0099270 ⚠
putative formin homology 2 (FH2) domain prote
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0110090 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0077210 ⚠
DNA replication licensing factor MCM3, putati
— OG7
TcYC6_0128020 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— OG7
TcYC6_0015950 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcYC6_0050600 ⚠
DNA replication licensing factor MCM7, putati
— OG7
TcYC6_0126910 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcYC6_0006510 ⚠
ubiquitin-domain-containing protein (fragment
— OG7
TcYC6_0106160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044050 ⚠
tubulin-tyrosine ligase-like protein
— OG7
TcYC6_0108120 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcYC6_0175620 ⚠
DNA replication licensing factor MCM8, putati
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0028610
hypothetical protein, conserved
— OG7
Page 1 of 3
Next →
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.