TcYC6_0095490

pdz domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_146793 OG7: OG7_0037550 198 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 198 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0045470
hypothetical protein, conserved
— Both
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0089660 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0042540 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcYC6_0103080 ⚠
Kinesin-13 5, putative
— OG7
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0070180 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
TcYC6_0097230
endosomal trafficking protein RME-8, putative
— Both
TcYC6_0079740
intraflagellar transport protein 122, putativ
— Both
TcYC6_0114770
putative intraflagellar transport protein 140
— Both
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— Both
TcYC6_0116430 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
TcYC6_0095570
CDC16, putative
— Both
TcYC6_0070220 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
TcYC6_0052960
cleavage and polyadenylation specificity fact
— Both
TcYC6_0111330 ⚠
radial spoke protein RSP10, putative
— Both
TcYC6_0107700
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TcYC6_0040230
AAA ATPase, putative
— Both
TcYC6_0060410 ⚠
cyclosome/APC complex protein, putative
— Both
TcYC6_0015530
Pre-mRNA polyadenylation factor FIP1
— Both
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— Both
TcYC6_0151050 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— Both
TcYC6_0152900 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0150680 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0099990
hypothetical protein
— OG6
TcYC6_0032440
hypothetical protein, conserved
— Both
TcYC6_0054780
transaldolase, putative
— Both
TcYC6_0057040
hypothetical protein, conserved
— Both
TcYC6_0025000
predicted tetratricopeptide repeat protein
— Both
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— Both
TcYC6_0113800
Flagellum attachment zone protein 7
— OG6
TcYC6_0012390
tRNA threonylcarbamoyl adenosine modification
— Both
TcYC6_0092460
SEP domain containing protein, putative
— Both
TcYC6_0030300
alanine racemase, putative
— Both
TcYC6_0045150
electron-transfer-flavoprotein, alpha polypep
— Both
TcYC6_0045140
Component of motile flagella 15
— Both
TcYC6_0094770
hypothetical protein, conserved
— Both
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcYC6_0124120 ⚠
Anaphase-promoting complex, cyclosome, subuni
— OG7
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— Both
TcYC6_0094210
ccr4-not transcription complex subunit
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.