TcYC6_0025000

predicted tetratricopeptide repeat protein
Trypanosoma cruzi Y C6 OG6: OG6_102882 OG7: OG7_0007593 140 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 140 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0021890 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— Both
TcYC6_0015530
Pre-mRNA polyadenylation factor FIP1
— Both
TcYC6_0097230
endosomal trafficking protein RME-8, putative
— Both
TcYC6_0070180 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
TcYC6_0054800 ⚠
hypothetical protein, conserved
— Both
TcYC6_0099230 ⚠
Sec7 domain containing protein, putative
— Both
TcYC6_0076120 ⚠
hypothetical protein, conserved
— Both
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— Both
TcYC6_0046210 ⚠
poly(p)/ATP NAD kinase, putative
— Both
TcYC6_0012040 ⚠
DNA replication licensing factor MCM6
— Both
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— Both
TcYC6_0043060
hypothetical protein, conserved
— Both
TcYC6_0111330 ⚠
radial spoke protein RSP10, putative
— Both
TcYC6_0042540 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0114830
hypothetical protein, conserved
— OG7
TcYC6_0002180 ⚠
hypothetical protein
— OG7
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0017100 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcYC6_0083610
hypothetical protein, conserved
— OG7
TcYC6_0043480
hypothetical protein, conserved
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0115610 ⚠
tubulin-specific chaperone, putative
— OG7
TcYC6_0127410
protein kinase, putative
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0090570 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0095280
hypothetical protein, conserved
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0037340 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016180
dynein heavy chain, putative
— OG7
TcYC6_0026390 ⚠
hypothetical protein
— OG7
TcYC6_0013180 ⚠
DNA replication licensing factor MCM2
— OG7
TcYC6_0077210 ⚠
DNA replication licensing factor MCM3, putati
— OG7
TcYC6_0036090 ⚠
DNA replication licensing factor MCM4, putati
— OG7
TcYC6_0175620 ⚠
DNA replication licensing factor MCM8, putati
— OG7
TcYC6_0050600 ⚠
DNA replication licensing factor MCM7, putati
— OG7
TcYC6_0071440 ⚠
DNA replication licensing factor MCM9, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.