TcYC6_0042180

Ankyrin repeats (3 copies), putative
Trypanosoma cruzi Y C6 OG6: OG6_133001 OG7: OG7_0000441 104 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 104 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0090760 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0052960 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0088170 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
TcYC6_0049490 ⚠
hypothetical protein
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0110650 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0026400 ⚠
hypothetical protein
— OG7
TcYC6_0109640 ⚠
RNA-binding protein, putative
— OG7
TcYC6_0114770 ⚠
putative intraflagellar transport protein 140
— OG7
TcYC6_0096930 ⚠
cyclosome subunit, putative
— OG7
TcYC6_0095280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0086190 ⚠
protein kinase-like protein, putative
— OG7
TcYC6_0075560 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0081840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0083620 ⚠
Nucleoporin NUP76
— OG7
TcYC6_0097230 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcYC6_0047940 ⚠
cytidine deaminase-like protein
— OG7
TcYC6_0016180 ⚠
dynein heavy chain, putative
— OG7
TcYC6_0076120 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0026390 ⚠
hypothetical protein
— OG7
TcYC6_0044060 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068380 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0046210 ⚠
poly(p)/ATP NAD kinase, putative
— OG7
TcYC6_0128060 ⚠
poly(p)/ATP NAD kinase, putative
— OG7
TcYC6_0084310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0125540 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
TcYC6_0000520 ⚠
ubiquitin-conjugating enzyme E2, putative
— OG7
TcYC6_0025000 ⚠
predicted tetratricopeptide repeat protein
— OG7
TcYC6_0101340 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
TcYC6_0082780 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0107270 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0052410 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0057690 ⚠
Protein of unknown function (DUF525), putativ
— OG7
TcYC6_0061620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0025540 ⚠
tRNA nucleotidyltransferase, putative
— OG7
TcYC6_0072020 ⚠
Tcc1i14-2.7
— OG7
TcYC6_0099210 ⚠
pitrilysin-like metalloprotease, putative
— OG7
TcYC6_0119370 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0069150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0126620 ⚠
developmentally regulated GTP-binding protein
— OG7
TcYC6_0022540 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— OG7
TcYC6_0115360 ⚠
RNA-binding protein 29, putative
— OG7
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0074910 ⚠
protein kinase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.