TcYC6_0090760

Programmed cell death protein 2, C-terminal putative domain containing protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_136955 OG7: OG7_0004545 72 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 72 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0099210 ⚠
pitrilysin-like metalloprotease, putative
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0095330 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
TcYC6_0031180 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcYC6_0074260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0096900 ⚠
hypothetical protein
— OG7
TcYC6_0077690 ⚠
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG7
TcYC6_0052410 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119370 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0057690 ⚠
Protein of unknown function (DUF525), putativ
— OG7
TcYC6_0069140 ⚠
putative ubiquitin-activating enzyme E1
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0028150 ⚠
general transcription factor IIB
— OG7
TcYC6_0068380 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044060 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072020 ⚠
Tcc1i14-2.7
— OG7
TcYC6_0045280 ⚠
mercaptopyruvate sulfurtransferase, putative
— OG7
TcYC6_0047950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— OG7
TcYC6_0101340 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
TcYC6_0107270 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0082780 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0025540 ⚠
tRNA nucleotidyltransferase, putative
— OG7
TcYC6_0012440 ⚠
D123, putative
— OG7
TcYC6_0078690 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
TcYC6_0088140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077270 ⚠
hypothetical protein
— OG7
TcYC6_0043980 ⚠
hypothetical protein
— OG7
TcYC6_0086170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0030520 ⚠
hypothetical protein
— OG7
TcYC6_0098810 ⚠
DNA ligase I, putative
— OG7
TcYC6_0012590 ⚠
Replication factor A protein 1
— OG7
TcYC6_0106020 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcYC6_0093680 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcYC6_0063850 ⚠
oxidoreductase, putative
— OG7
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0076700 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
TcYC6_0102100 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0009400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0071890 ⚠
ribosome-interacting GTPase 2, putative
— OG7
TcYC6_0126620 ⚠
developmentally regulated GTP-binding protein
— OG7
TcYC6_0111560 ⚠
Ubiquitin-like domain containing protein, put
— OG7
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0063970 ⚠
oxidoreductase, putative
— OG7
TcYC6_0069150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053450 ⚠
ethanolamine-phosphate cytidylyltransferase
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.