TcYC6_0009400

mitochondrial processing peptidase alpha subunit, putative
Trypanosoma cruzi Y C6 OG6: OG6_155541 OG7: OG7_0001887 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0059630 ⚠
thimet oligopeptidase, putative
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— OG7
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0123640 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053450 ⚠
ethanolamine-phosphate cytidylyltransferase
— OG7
TcYC6_0071890 ⚠
ribosome-interacting GTPase 2, putative
— OG7
TcYC6_0042180 ⚠
Ankyrin repeats (3 copies), putative
— OG7
TcYC6_0109080 ⚠
cytochrome b5, putative
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0072020 ⚠
Tcc1i14-2.7
— OG7
TcYC6_0043870 ⚠
cytochrome b5
— OG7
TcYC6_0043620 ⚠
anion-transporting ATPase-like, putative
— OG7
TcYC6_0057690 ⚠
Protein of unknown function (DUF525), putativ
— OG7
TcYC6_0086410 ⚠
kynureninase, putative
— OG7
TcYC6_0119730 ⚠
metallo-peptidase, Clan MG, Family M24, putat
— OG7
TcYC6_0049170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0128170 ⚠
serine sulfhydrylase
— OG7
TcYC6_0012450 ⚠
Small Surface Antigen
— OG7
TcYC6_0115830 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0040300 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcYC6_0040350 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcYC6_0009920 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcYC6_0100460 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0110350 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
TcYC6_0081540 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0078640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0093270 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcYC6_0022540 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0052970 ⚠
PPPDE putative peptidase domain containing pr
— OG7
TcYC6_0079830 ⚠
SNF1-related protein kinase, putative
— OG7
TcYC6_0077270 ⚠
hypothetical protein
— OG7
TcYC6_0025540 ⚠
tRNA nucleotidyltransferase, putative
— OG7
TcYC6_0095430 ⚠
nitrate reductase, putative
— OG7
TcYC6_0125540 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
TcYC6_0115360 ⚠
RNA-binding protein 29, putative
— OG7
TcYC6_0007280 ⚠
S-adenosylhomocysteine hydrolase, putative
— OG7
TcYC6_0058570 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcYC6_0090760 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0107270 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044440 ⚠
serine sulfhydrylase
— OG7
TcYC6_0044910 ⚠
serine sulfhydrylase
— OG7
TcYC6_0074260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0099210 ⚠
pitrilysin-like metalloprotease, putative
— OG7
TcYC6_0068380 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0081110 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.