TcYC6_0074260

hypothetical protein, conserved
Trypanosoma cruzi Y C6 OG6: OG6_388959 OG7: OG7_0063820 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0045280
mercaptopyruvate sulfurtransferase, putative
— Both
TcYC6_0066650 ⚠
putative tubulin tyrosine ligase
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0102710
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
TcYC6_0016680 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0044050 ⚠
tubulin-tyrosine ligase-like protein
— OG7
TcYC6_0108120 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcYC6_0071460 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0054430 ⚠
tubulin tyrosine ligase, putative
— OG7
TcYC6_0077690
tyrosyl-DNA Phosphodiesterase (Tdp1), putativ
— OG7
TcYC6_0075700 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcYC6_0115520 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcYC6_0063720 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0063730 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0066660 ⚠
hypothetical protein
— OG7
TcYC6_0097300 ⚠
tubulin-tyrosine ligase-like protein, putativ
— OG7
TcYC6_0063740 ⚠
ribonuclease mar1, putative
— OG7
TcYC6_0086170
hypothetical protein, conserved
— OG7
TcYC6_0102100 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0043980 ⚠
hypothetical protein
— OG7
TcYC6_0022540 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0090760 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
TcYC6_0099210
pitrilysin-like metalloprotease, putative
— OG7
TcYC6_0028150
general transcription factor IIB
— OG7
TcYC6_0123640 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcYC6_0078690 ⚠
cytosolic nonspecific dipeptidase, putative
— OG7
TcYC6_0012440
D123, putative
— OG7
TcYC6_0088140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0009400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0098810
DNA ligase I, putative
— OG7
TcYC6_0012590
Replication factor A protein 1
— OG7
TcYC6_0106020 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcYC6_0098470
valyl-tRNA synthetase, putative
— OG7
TcYC6_0072330
hypothetical protein, conserved
— OG7
TcYC6_0095330
N-acetyltransferase B complex (NatB) non cata
— OG7
TcYC6_0096900
hypothetical protein
— OG7
TcYC6_0006570 ⚠
cysteine synthase, putative
— OG6
TcYC6_0095430 ⚠
nitrate reductase, putative
— Both
TcYC6_0007280
S-adenosylhomocysteine hydrolase, putative
— Both
TcYC6_0078980 ⚠
mitogen-activated protein kinase 11, putative
— OG6
TcYC6_0113080 ⚠
mitogen activated protein kinase 2, putative
— OG6
TcYC6_0119730
metallo-peptidase, Clan MG, Family M24, putat
— Both
TcYC6_0119620
urocanate hydratase, putative
— Both
TcYC6_0074940
protein phosphatase 2C, putative
— OG6
TcYC6_0072520
UDP-galactose 4-epimerase, putative
— Both
TcYC6_0100380
phosphoacetylglucosamine mutase, putative
— Both
TcYC6_0059630 ⚠
thimet oligopeptidase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.