TcYC6_0078980

mitogen-activated protein kinase 11, putative
Trypanosoma cruzi Y C6 OG6: OG6_100339 OG7: OG7_0000396 30 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 30 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0059630 ⚠
thimet oligopeptidase, putative
— OG6
TcYC6_0076460 ⚠
trypanothione synthetase
— OG6
TcYC6_0037100 ⚠
Uncharacterised protein family (UPF0160), put
— OG6
TcYC6_0074940 ⚠
protein phosphatase 2C, putative
— OG6
TcYC6_0076700 ⚠
Mitochondrial-processing peptidase subunit al
— OG6
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG6
TcYC6_0097500 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0097570 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0045280 ⚠
mercaptopyruvate sulfurtransferase, putative
— OG6
TcYC6_0100380 ⚠
phosphoacetylglucosamine mutase, putative
— OG6
TcYC6_0072520 ⚠
UDP-galactose 4-epimerase, putative
— OG6
TcYC6_0119620 ⚠
urocanate hydratase, putative
— OG6
TcYC6_0005610 ⚠
translation initiation factor 2 subunit, puta
— OG6
TcYC6_0119730 ⚠
metallo-peptidase, Clan MG, Family M24, putat
— OG6
TcYC6_0115610 ⚠
tubulin-specific chaperone, putative
— OG6
TcYC6_0044880 ⚠
serine sulfhydrylase
— OG6
TcYC6_0000710 ⚠
imidazolonepropionase, putative
— OG6
TcYC6_0121450 ⚠
prolyl endopeptidase
— OG6
TcYC6_0007280 ⚠
S-adenosylhomocysteine hydrolase, putative
— OG6
TcYC6_0095430 ⚠
nitrate reductase, putative
— OG6
TcYC6_0074260 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0006570 ⚠
cysteine synthase, putative
— OG6
TcYC6_0128170 ⚠
serine sulfhydrylase
— OG6
TcYC6_0044870 ⚠
serine sulfhydrylase
— OG6
TcYC6_0044900 ⚠
serine sulfhydrylase
— OG6
TcYC6_0046320 ⚠
serine sulfhydrylase
— OG6
TcYC6_0044890 ⚠
serine sulfhydrylase
— OG6
TcYC6_0175670 ⚠
hypothetical protein
— OG6
TcYC6_0044440 ⚠
serine sulfhydrylase
— OG6
TcYC6_0044910 ⚠
serine sulfhydrylase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.