TcYC6_0044880

serine sulfhydrylase
Trypanosoma cruzi Y C6 OG6: OG6_100154 OG7: OG7_0002172 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0031310 ⚠
acetyl-CoA synthetase, putative
— +1 more Both
TcYC6_0058320 ⚠
asparagine synthetase a, putative
— Both
TcYC6_0100380 ⚠
phosphoacetylglucosamine mutase, putative
— +2 more Both
TcYC6_0076460 ⚠
trypanothione synthetase
— Both
TcYC6_0107640 ⚠
nucleolar protein, putative
— OG7
TcYC6_0046060 ⚠
hypothetical protein
— OG6
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0102100 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0009400 ⚠
mitochondrial processing peptidase alpha subu
— OG7
TcYC6_0037100 ⚠
Uncharacterised protein family (UPF0160), put
— OG6
TcYC6_0076700 ⚠
Mitochondrial-processing peptidase subunit al
— Both
TcYC6_0083900 ⚠
2-amino-3-ketobutyrate coenzyme A ligase, put
— Both
TcYC6_0096260 ⚠
pyridoxal kinase, putative
— Both
TcYC6_0083800 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TcYC6_0017390 ⚠
cytidine triphosphate synthase, putative
— Both
TcYC6_0083870 ⚠
2-amino-3-ketobutyrate coenzyme A ligase, put
— Both
TcYC6_0031010 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
TcYC6_0024870 ⚠
spermidine synthase, putative
— Both
TcYC6_0025040 ⚠
spermidine synthase, putative
— Both
TcYC6_0011340 ⚠
cytosolic malate dehydrogenase, putative
— Both
TcYC6_0110640 ⚠
Aminopeptidase M1, putative
— Both
TcYC6_0019520 ⚠
threonine synthase, putative
— Both
TcYC6_0036970 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
TcYC6_0121550 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0111240 ⚠
inosine-adenosine-guanosine-nucleosidehydrola
— Both
TcYC6_0058570 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcYC6_0046750 ⚠
serine palmitoyltransferase, putative
— OG7
TcYC6_0098700 ⚠
hypothetical protein, conserved
— Both
TcYC6_0109080 ⚠
cytochrome b5, putative
— OG7
TcYC6_0043870 ⚠
cytochrome b5
— OG7
TcYC6_0049170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040620 ⚠
cytochrome b5, putative
— OG7
TcYC6_0123640 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
TcYC6_0091000 ⚠
serine-palmitoyl-CoA transferase
— OG7
TcYC6_0120330 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0102720 ⚠
aminopeptidase
— OG7
TcYC6_0031400 ⚠
trypanothione synthetase, putative
— OG7
TcYC6_0077370 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0014080 ⚠
NOL1/NOP2/sun family, putative
— OG7
TcYC6_0077360 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TcYC6_0060080 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
TcYC6_0103660 ⚠
aminopeptidase
— OG7
TcYC6_0099250 ⚠
putative nonspecific lipid-transfer protein
— OG7
TcYC6_0120660 ⚠
glutathionylspermidine synthase, putative
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0088810 ⚠
Protein of unknown function (DUF3808), putati
— OG7
TcYC6_0086100 ⚠
methyltransferase domain containing protein,
— OG7
TcYC6_0030870 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0110330 ⚠
NOL1/NOP2/sun family, putative
— OG7
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.