TcYC6_0123640

mitochondrial intermediate peptidase, putative
Trypanosoma cruzi Y C6 OG6: OG6_102110 OG7: OG7_0002961 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0072740 ⚠
UDP-N-acetylglucosamine pyrophosphorylase
— Both
TcYC6_0007280 ⚠
S-adenosylhomocysteine hydrolase, putative
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0119620 ⚠
urocanate hydratase, putative
— OG7
TcYC6_0027820 ⚠
myo-inositol-1 phosphatase
— OG7
TcYC6_0175670 ⚠
hypothetical protein
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0012100 ⚠
elongation factor G2-like protein, putative
— OG7
TcYC6_0044890 ⚠
serine sulfhydrylase
— OG7
TcYC6_0097570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0045280 ⚠
mercaptopyruvate sulfurtransferase, putative
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0040620 ⚠
cytochrome b5, putative
— OG7
TcYC6_0046320 ⚠
serine sulfhydrylase
— OG7
TcYC6_0044900 ⚠
serine sulfhydrylase
— OG7
TcYC6_0044870 ⚠
serine sulfhydrylase
— OG7
TcYC6_0095870 ⚠
adenosine kinase, putative
— OG7
TcYC6_0054550 ⚠
aspartate carbamoyltransferase, putative
— OG7
TcYC6_0128170 ⚠
serine sulfhydrylase
— OG7
TcYC6_0049170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119730 ⚠
metallo-peptidase, Clan MG, Family M24, putat
— OG7
TcYC6_0043870 ⚠
cytochrome b5
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0012480 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0109080 ⚠
cytochrome b5, putative
— OG7
TcYC6_0058570 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcYC6_0024870 ⚠
spermidine synthase, putative
— OG7
TcYC6_0037010 ⚠
oligopeptidase b
— OG7
TcYC6_0121450 ⚠
prolyl endopeptidase
— OG7
TcYC6_0013810 ⚠
serine peptidase, clan SC, family S9A-like pr
— OG7
TcYC6_0072350 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0036070 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
TcYC6_0099360 ⚠
protein phosphatase 2A, regulatory subunit B,
— OG7
TcYC6_0084140 ⚠
Eukaryotic initiation factor 4A-1
— OG7
TcYC6_0034510 ⚠
ecotin, putative
— OG7
TcYC6_0094150 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcYC6_0101180 ⚠
Metallopeptidase family M24, putative
— OG7
TcYC6_0021830 ⚠
ATP-dependent RNA helicase SUB2, putative
— OG7
TcYC6_0112730 ⚠
malate dehydrogenase
— OG7
TcYC6_0175560 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0095430 ⚠
nitrate reductase, putative
— OG7
TcYC6_0090820 ⚠
adenosine kinase, putative
— OG7
TcYC6_0106870 ⚠
kinetoplastid-specific phospho-protein phosph
— OG7
TcYC6_0014130 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
TcYC6_0113780 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcYC6_0045560 ⚠
deoxyribose-phosphate aldolase, putative
— OG7
TcYC6_0121630 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0025040 ⚠
spermidine synthase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.