TcYC6_0119620

urocanate hydratase, putative

Trypanosoma cruzi Y C6 OG6: OG6_105382 OG7: OG7_0011182 35 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 35 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0109080 ⚠ cytochrome b5, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_006380	OG7
TcYC6_0007280 S-adenosylhomocysteine hydrolase, putative	—	OG6 TCSYLVIO_006380 ↔ TCSYLVIO_009217 OG7 TCSYLVIO_006380 ↔ TCSYLVIO_009217	Both
TcYC6_0072520 UDP-galactose 4-epimerase, putative	—	OG6 TCSYLVIO_005587 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_005587 ↔ TCSYLVIO_006380	Both
TcYC6_0045280 mercaptopyruvate sulfurtransferase, putative	—	OG6 TCSYLVIO_001928 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001928 ↔ TCSYLVIO_006380	Both
TcYC6_0097570 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003285 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_003285 ↔ TCSYLVIO_006380	Both
TcYC6_0097500 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003285 ↔ TCSYLVIO_006380	OG6
TcYC6_0101710 ⚠ protein kinase A regulatory subunit	—	OG6 TCSYLVIO_002171 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002171 ↔ TCSYLVIO_006380	Both
TcYC6_0076700 ⚠ Mitochondrial-processing peptidase subunit al	—	OG6 TCSYLVIO_000413 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_000413 ↔ TCSYLVIO_006380	Both
TcYC6_0040620 ⚠ cytochrome b5, putative	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_006380	OG7
TcYC6_0078980 ⚠ mitogen-activated protein kinase 11, putative	—	OG6 TCSYLVIO_006380 ↔ TCSYLVIO_010076	OG6
TcYC6_0058570 ⚠ cytochrome b5-like Heme/Steroid binding domai	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_006380	OG7
TcYC6_0049170 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_006380	OG7
TcYC6_0043870 ⚠ cytochrome b5	—	OG7 TCSYLVIO_003124 ↔ TCSYLVIO_006380	OG7
TcYC6_0009400 ⚠ mitochondrial processing peptidase alpha subu	—	OG7 TCSYLVIO_000413 ↔ TCSYLVIO_006380	OG7
TcYC6_0102100 ⚠ mitochondrial processing peptidase alpha subu	—	OG7 TCSYLVIO_000413 ↔ TCSYLVIO_006380	OG7
TcYC6_0049440 ⚠ cyclic nucleotide-binding protein	—	OG7 TCSYLVIO_002171 ↔ TCSYLVIO_006380	OG7
TcYC6_0089970 ⚠ regulatory subunit of protein kinase a-like p	—	OG7 TCSYLVIO_002171 ↔ TCSYLVIO_006380	OG7
TcYC6_0123640 ⚠ mitochondrial intermediate peptidase, putativ	—	OG7 TCSYLVIO_000949 ↔ TCSYLVIO_006380	OG7
TcYC6_0006570 ⚠ cysteine synthase, putative	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380	OG6
TcYC6_0044910 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0044440 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0175670 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0044890 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0046320 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0044900 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0044870 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0128170 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0044880 ⚠ serine sulfhydrylase	—	OG6 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG6 TCSYLVIO_001774 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_002234 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_001774 ↔ TCSYLVIO_006380	Both
TcYC6_0074260 hypothetical protein, conserved	—	OG6 TCSYLVIO_005467 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_005467 ↔ TCSYLVIO_006380	Both
TcYC6_0095430 ⚠ nitrate reductase, putative	—	OG6 TCSYLVIO_003124 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_003124 ↔ TCSYLVIO_006380	Both
TcYC6_0059630 ⚠ thimet oligopeptidase, putative	—	OG6 TCSYLVIO_000949 ↔ TCSYLVIO_006380 OG7 TCSYLVIO_000949 ↔ TCSYLVIO_006380	Both
TcYC6_0100380 phosphoacetylglucosamine mutase, putative	—	OG6 TCSYLVIO_006380 ↔ TCSYLVIO_009729 OG7 TCSYLVIO_006380 ↔ TCSYLVIO_009729	Both
TcYC6_0074940 protein phosphatase 2C, putative	—	OG6 TCSYLVIO_006380 ↔ TCSYLVIO_007410	OG6
TcYC6_0119730 metallo-peptidase, Clan MG, Family M24, putat	—	OG6 TCSYLVIO_006380 ↔ TCSYLVIO_006389 OG7 TCSYLVIO_006380 ↔ TCSYLVIO_006389	Both
TcYC6_0113080 ⚠ mitogen activated protein kinase 2, putative	—	OG6 TCSYLVIO_006380 ↔ TCSYLVIO_010076	OG6