TcYC6_0101710

protein kinase A regulatory subunit
Trypanosoma cruzi Y C6 OG6: OG6_100449 OG7: OG7_0001574 166 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 166 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0022750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0066360 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcYC6_0088960 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0119510 ⚠
General negative regulator of transcription s
— OG7
TcYC6_0078830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0002180 ⚠
hypothetical protein
— OG7
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0075070 ⚠
hypothetical protein
— OG7
TcYC6_0090250 ⚠
phosphatidylinositol phosphate kinase alpha
— OG7
TcYC6_0071240 ⚠
lipoic acid containing carrier protein, putat
— OG7
TcYC6_0094770 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044010 ⚠
regulator of chromatin condensation, putative
— OG7
TcYC6_0058600 ⚠
putative dynein arm light chain
— OG7
TcYC6_0083610 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0017100 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcYC6_0109670 ⚠
Cell growth-regulating nucleolar protein, put
— OG7
TcYC6_0125590 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
TcYC6_0071260 ⚠
regulator of chromosome condensation (RCC1),
— OG7
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0115610 ⚠
tubulin-specific chaperone, putative
— OG7
TcYC6_0127410 ⚠
protein kinase, putative
— OG7
TcYC6_0090570 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0012640 ⚠
Serine/threonine-protein kinase VPS15, putati
— OG7
TcYC6_0068720 ⚠
ankyrin repeat protein, putative
— OG7
TcYC6_0016330 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0021890 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0104160 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TcYC6_0047800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0114430 ⚠
fibrillarin, putative
— OG7
TcYC6_0113590 ⚠
putative Associated kinase of Tb14-3-3
— OG7
TcYC6_0017740 ⚠
DNA-directed RNA polymerase 2, RPB12 subunit,
— OG7
TcYC6_0052960 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0056280 ⚠
putative regulator of chromosome condensation
— OG7
TcYC6_0046800 ⚠
phosphatidylinositol-4-phosphate 5-kinase-lik
— OG7
TcYC6_0059590 ⚠
hypothetical protein
— OG7
TcYC6_0075560 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0097230 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcYC6_0080390 ⚠
phosphatidylinositol-4-phosphate 5-kinase, pu
— OG7
TcYC6_0081840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0083620 ⚠
Nucleoporin NUP76
— OG7
TcYC6_0116450 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0037340 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.