TcYC6_0075560

cleavage and polyadenylation specificity factor, putative
Trypanosoma cruzi Y C6 OG6: OG6_103283 OG7: OG7_0002417 165 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 165 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0090570 ⚠
cleavage and polyadenylation specificity fact
— Both
TcYC6_0049170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022740 ⚠
methionyl-tRNA synthetase, putative
— Both
TcYC6_0120060 ⚠
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0074690 ⚠
hypothetical protein
— Both
TcYC6_0027170 ⚠
hypothetical protein
— Both
TcYC6_0074840 ⚠
protein kinase
— Both
TcYC6_0094080 ⚠
alanyl-tRNA synthetase, putative
— Both
TcYC6_0110440 ⚠
UDP-glucose:glycoprotein glucosyltransferase
— Both
TcYC6_0000250 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0060410 ⚠
cyclosome/APC complex protein, putative
— Both
TcYC6_0040230 ⚠
AAA ATPase, putative
— Both
TcYC6_0042390 ⚠
hypothetical protein, conserved
— Both
TcYC6_0081840 ⚠
hypothetical protein, conserved
— Both
TcYC6_0122980 ⚠
isoleucyl-tRNA synthetase, putative
— Both
TcYC6_0044850 ⚠
exosome complex exonuclease RRP44p-like
— OG7
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0088420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0037340 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0010370 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0004090 ⚠
ABC transporter, putative
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0010170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0006180 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcYC6_0095530 ⚠
nuclear movement protein, putative
— OG7
TcYC6_0040620 ⚠
cytochrome b5, putative
— OG7
TcYC6_0106020 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcYC6_0055270 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0024170 ⚠
ABC transporter, putative
— OG7
TcYC6_0029650 ⚠
ABC transporter, putative
— OG7
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0002740 ⚠
ABC transporter, putative
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0092990 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0109080 ⚠
cytochrome b5, putative
— OG7
TcYC6_0058570 ⚠
cytochrome b5-like Heme/Steroid binding domai
— OG7
TcYC6_0017100 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
TcYC6_0095280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0026400 ⚠
hypothetical protein
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0103780 ⚠
Flagellum attachment zone protein 14
— OG7
TcYC6_0127410 ⚠
protein kinase, putative
— OG7
TcYC6_0109430 ⚠
Ankyrin repeats (many copies)/Ankyrin repeats
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.