TcYC6_0074840

protein kinase
Trypanosoma cruzi Y C6 OG6: OG6_101388 OG7: OG7_0005083 166 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 166 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0071020
hypothetical protein, conserved
— Both
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0044850 ⚠
exosome complex exonuclease RRP44p-like
— OG7
TcYC6_0127080
inositol-3-phosphate synthase, putative
— Both
TcYC6_0005360 ⚠
amidohydrolase, putative
— OG7
TcYC6_0043290 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcYC6_0043280 ⚠
pyruvate phosphate dikinase, putative
— OG7
TcYC6_0058520 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0041950 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0015520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072620 ⚠
GTPase protein
— OG7
TcYC6_0071810 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0117560
hypothetical protein, conserved
— OG7
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0054390 ⚠
Met-10+ like-protein, putative
— OG7
TcYC6_0004150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0075720 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcYC6_0086070 ⚠
serine/threonine protein kinase
— OG7
TcYC6_0113920 ⚠
protein kinase
— OG7
TcYC6_0086030 ⚠
serine/threonine protein kinase
— OG7
TcYC6_0120980 ⚠
hypothetical protein
— OG7
TcYC6_0086080 ⚠
serine/threonine protein kinase
— OG7
TcYC6_0086020 ⚠
serine/threonine protein kinase, putative
— OG7
TcYC6_0047690 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcYC6_0000950
histone H4, putative
— OG7
TcYC6_0095150 ⚠
rab6 GTPase activating protein, putative
— OG7
TcYC6_0122510 ⚠
rab-like GTPase activating protein, putative
— OG7
TcYC6_0095260
hypothetical protein, conserved
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0096550
phosphopantothenoylcysteine decarboxylase, pu
— OG7
TcYC6_0142810 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0010370 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0142880 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0095530 ⚠
nuclear movement protein, putative
— OG7
TcYC6_0106020 ⚠
dihydrouridine synthase (Dus), putative
— OG7
TcYC6_0055270 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— OG7
TcYC6_0080270 ⚠
dihydrouridine synthase, putative
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0092990 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0088140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106460
hypothetical protein, conserved
— OG7
TcYC6_0049110
methyltransferase domain containing protein,
— OG7
TcYC6_0069010 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0083520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0120140
hypothetical protein, conserved
— OG7
TcYC6_0116460 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.