TcYC6_0005360

amidohydrolase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101553 OG7: OG7_0005942 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— +9 more Both
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— +7 more Both
TcYC6_0044850 ⚠
exosome complex exonuclease RRP44p-like
— +1 more Both
TcYC6_0122980 ⚠
isoleucyl-tRNA synthetase, putative
— Both
TcYC6_0024770 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TcYC6_0113000 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
TcYC6_0057340 ⚠
Cupin-like domain containing protein, putativ
— Both
TcYC6_0088430 ⚠
EAP30/Vps36 family, putative
— Both
TcYC6_0106460 ⚠
hypothetical protein, conserved
— Both
TcYC6_0072940 ⚠
hypothetical protein, conserved
— Both
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0098400 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— Both
TcYC6_0082070 ⚠
putative pre-mRNA-splicing factor ATP-depende
— OG6
TcYC6_0067410 ⚠
U3 small nucleolar RNA-associated protein 6,
— Both
TcYC6_0108430 ⚠
ABC transporter, putative
— Both
TcYC6_0103240 ⚠
putative ABC transporter
— Both
TcYC6_0043090 ⚠
putative ATP-binding cassette transporter ABC
— Both
TcYC6_0028620 ⚠
ABC transporter, putative
— Both
TcYC6_0112720 ⚠
malate dehydrogenase, putative
— Both
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0023910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0095660 ⚠
co-chaperone GrpE, putative
— Both
TcYC6_0016660 ⚠
conserved protein, unknown function
— Both
TcYC6_0110400 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0090640 ⚠
ruvB-like DNA helicase, putative
— OG7
TcYC6_0053140 ⚠
hypothetical protein
— OG7
TcYC6_0058520 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0041950 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0072620 ⚠
GTPase protein
— OG7
TcYC6_0071810 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0002790 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0004150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113780 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcYC6_0112730 ⚠
malate dehydrogenase
— OG7
TcYC6_0016610 ⚠
Quinonprotein alcohol dehydrogenase-like prot
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0019430 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0093940 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
TcYC6_0034710 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0124540 ⚠
heat shock protein 85, putative
— OG7
TcYC6_0121770 ⚠
protein transport protein SEC23
— OG7
TcYC6_0074850 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095530 ⚠
nuclear movement protein, putative
— OG7
TcYC6_0053520 ⚠
CYC2-like cyclin 6, putative
— OG7
TcYC6_0024720 ⚠
putative RNA pseudouridylate synthase protein
— OG7
TcYC6_0069180 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcYC6_0108590 ⚠
heat shock protein 90, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.