TcYC6_0089430

asparaginyl-tRNA synthetase, putative
Trypanosoma cruzi Y C6 OG6: OG6_103052 OG7: OG7_0002299 329 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 329 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0061240 ⚠
hypothetical protein, conserved
— +2 more Both
TcYC6_0061260 ⚠
helicase, putative
— +2 more Both
TcYC6_0061280 ⚠
helicase, putative
— +2 more Both
TcYC6_0061220 ⚠
helicase, putative
— +2 more Both
TcYC6_0122980 ⚠
isoleucyl-tRNA synthetase, putative
— +1 more Both
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— Both
TcYC6_0044260 ⚠
acidocalcisomal pyrophosphatase, putative
— Both
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— Both
TcYC6_0019430 ⚠
tyrosyl-tRNA synthetase, putative
— Both
TcYC6_0072920 ⚠
phenylalanyl-tRNA synthetase (beta subunit),
— Both
TcYC6_0062380 ⚠
threonyl-tRNA synthetase, putative
— Both
TcYC6_0065870 ⚠
hypothetical protein, conserved
— Both
TcYC6_0116560 ⚠
prolyl-tRNA synthetase, putative
— +1 more Both
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0095370 ⚠
hypothetical protein, conserved
— Both
TcYC6_0010370 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— Both
TcYC6_0055270 ⚠
tyrosyl or methionyl-tRNA synthetase, putativ
— Both
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0092990 ⚠
hypothetical protein, conserved
— Both
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— +1 more Both
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0073450 ⚠
arginyl-tRNA synthetase, putative
— OG7
TcYC6_0079620 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
TcYC6_0095150 ⚠
rab6 GTPase activating protein, putative
— OG7
TcYC6_0102190 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcYC6_0123030 ⚠
beta adaptin, putative
— OG7
TcYC6_0011810 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0075720 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
TcYC6_0124530 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcYC6_0116460 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TcYC6_0086540 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0123270 ⚠
branch point binding protein, putative
— OG7
TcYC6_0009200 ⚠
Lupus La protein-like, putative
— OG7
TcYC6_0112560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0096590 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcYC6_0042410 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0005350 ⚠
aminoacylase, putative
— OG7
TcYC6_0021670 ⚠
ATP synthase, putative
— OG7
TcYC6_0021990 ⚠
protein kinase PK4, putative
— OG7
TcYC6_0070640 ⚠
synaptojanin (N-terminal domain), putative
— OG7
TcYC6_0005340 ⚠
amidohydrolase, putative
— OG7
TcYC6_0004090 ⚠
ABC transporter, putative
— OG7
TcYC6_0043300 ⚠
beta-adaptin 1, putative
— OG7
TcYC6_0059460 ⚠
pseudouridylate synthase I, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.