TcYC6_0089430

asparaginyl-tRNA synthetase, putative

Trypanosoma cruzi Y C6 OG6: OG6_103052 OG7: OG7_0002299 329 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 329 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcYC6_0061240 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_120255.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG6 Tb927.4.2310 ↔ Tb927.6.950 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 +2 more	Both
TcYC6_0061260 ⚠ helicase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG6 Tb927.4.2310 ↔ Tb927.6.950 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 +2 more	Both
TcYC6_0061280 ⚠ helicase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG6 Tb927.4.2310 ↔ Tb927.6.950 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 +2 more	Both
TcYC6_0061220 ⚠ helicase, putative	—	OG6 LdBPK_120255.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_006977 OG6 Tb927.4.2310 ↔ Tb927.6.950 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006977 +2 more	Both
TcYC6_0122980 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 Tb927.10.9190 ↔ Tb927.4.2310 OG6 TCSYLVIO_003867 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004705 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004705 +1 more	Both
TcYC6_0068420 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003867 OG7 LdBPK_230660.1 ↔ LdBPK_342110.1	OG7
TcYC6_0091190 ⚠ Histidine kinase-, DNA gyrase B-, and HSP90-l	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	OG7
TcYC6_0111400 ⚠ inorganic pyrophosphatase, putative	—	OG6 Tb927.11.7060 ↔ Tb927.4.2310 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003867 OG7 Tb927.11.7060 ↔ Tb927.4.2310 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003867	Both
TcYC6_0044260 ⚠ acidocalcisomal pyrophosphatase, putative	—	OG6 Tb927.11.7060 ↔ Tb927.4.2310 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_003867 OG7 Tb927.11.7060 ↔ Tb927.4.2310 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_003867	Both
TcYC6_0017360 ⚠ putative developmentally regulated phosphopro	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001571 ↔ TCSYLVIO_003867	Both
TcYC6_0019430 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_003107 OG7 Tb927.4.2310 ↔ Tb927.8.5330	Both
TcYC6_0072920 ⚠ phenylalanyl-tRNA synthetase (beta subunit),	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG6 LdBPK_191010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005548 OG7 LdBPK_191010.1 ↔ LdBPK_342110.1	Both
TcYC6_0062380 ⚠ threonyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_007511 OG6 Tb927.4.2310 ↔ Tb927.5.1090 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007511 OG7 Tb927.4.2310 ↔ Tb927.5.1090	Both
TcYC6_0065870 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_342110.1	Both
TcYC6_0116560 ⚠ prolyl-tRNA synthetase, putative	—	OG6 LdBPK_181220.1 ↔ LdBPK_342110.1 OG6 LdBPK_181230.1 ↔ LdBPK_342110.1 OG7 LdBPK_181220.1 ↔ LdBPK_342110.1 OG7 LdBPK_181230.1 ↔ LdBPK_342110.1 +1 more	Both
TcYC6_0072780 ⚠ aminopeptidase, putative,metallo-peptidase, C	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
TcYC6_0095370 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_300580.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_003118 ↔ TCSYLVIO_003867 OG7 LdBPK_300580.1 ↔ LdBPK_342110.1	Both
TcYC6_0010370 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 Tb927.4.2310 ↔ Tb927.8.5330 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_003107 OG7 Tb927.4.2310 ↔ Tb927.8.5330	Both
TcYC6_0055270 ⚠ tyrosyl or methionyl-tRNA synthetase, putativ	—	OG6 Tb927.4.2310 ↔ Tb927.8.5330 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_003107 OG7 Tb927.4.2310 ↔ Tb927.8.5330	Both
TcYC6_0080930 ⚠ pyruvate dehydrogenase (lipoamide) kinase, pu	—	OG6 TCSYLVIO_001571 ↔ TCSYLVIO_003867 OG6 LdBPK_240010.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007262 OG7 LdBPK_240010.1 ↔ LdBPK_342110.1 +1 more	Both
TcYC6_0043810 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG6 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 +1 more	Both
TcYC6_0031230 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_230660.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003867 OG7 LdBPK_230660.1 ↔ LdBPK_342110.1	Both
TcYC6_0092990 ⚠ hypothetical protein, conserved	—	OG6 Tb927.4.2310 ↔ Tb927.8.5330 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_003107 OG7 Tb927.4.2310 ↔ Tb927.8.5330	Both
TcYC6_0083670 ⚠ tubulin folding cofactor D, putative	—	OG6 LdBPK_242100.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_001302 ↔ TCSYLVIO_003867 OG7 LdBPK_242100.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001302 ↔ TCSYLVIO_003867 +1 more	Both
TcYC6_0121920 ⚠ poly(A)-specific ribonuclease PARN, putative	—	OG6 LdBPK_230660.1 ↔ LdBPK_342110.1 OG6 TCSYLVIO_000055 ↔ TCSYLVIO_003867 OG7 TCSYLVIO_000055 ↔ TCSYLVIO_003867 OG7 LdBPK_230660.1 ↔ LdBPK_342110.1	Both
TcYC6_0073450 ⚠ arginyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005509	OG7
TcYC6_0079620 ⚠ endonuclease/exonuclease/phosphatase, putativ	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007569	OG7
TcYC6_0095150 ⚠ rab6 GTPase activating protein, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004663	OG7
TcYC6_0102190 ⚠ N(2), N(2)-dimethylguanosine tRNA methyltrans	—	OG7 TCSYLVIO_002844 ↔ TCSYLVIO_003107	OG7
TcYC6_0073050 ⚠ Eukaryotic translation initiation factor 4E-1	—	OG7 LdBPK_300460.1 ↔ LdBPK_342110.1	OG7
TcYC6_0123030 ⚠ beta adaptin, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004597	OG7
TcYC6_0011810 ⚠ Eukaryotic translation initiation factor 4E-3	—	OG7 LdBPK_300460.1 ↔ LdBPK_342110.1	OG7
TcYC6_0113040 ⚠ eukaryotic translation initiation factor 4E (	—	OG7 LdBPK_300460.1 ↔ LdBPK_342110.1	OG7
TcYC6_0075720 ⚠ calcium/calmodulin-dependent protein kinase,	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_005149	OG7
TcYC6_0124530 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006012	OG7
TcYC6_0116460 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004998 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004998	OG7
TcYC6_0086540 ⚠ WD domain, G-beta repeat, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005180	OG7
TcYC6_0123270 ⚠ branch point binding protein, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004728	OG7
TcYC6_0009200 ⚠ Lupus La protein-like, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006827	OG7
TcYC6_0112560 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004376	OG7
TcYC6_0096590 ⚠ pseudouridine synthase A-like protein, putati	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004376	OG7
TcYC6_0042410 ⚠ zinc-finger of a C2HC-type, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_006138	OG7
TcYC6_0005350 ⚠ aminoacylase, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	OG7
TcYC6_0021670 ⚠ ATP synthase, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_009332	OG7
TcYC6_0021990 ⚠ protein kinase PK4, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_009362	OG7
TcYC6_0070640 ⚠ synaptojanin (N-terminal domain), putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007569	OG7
TcYC6_0005340 ⚠ amidohydrolase, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_008414	OG7
TcYC6_0004090 ⚠ ABC transporter, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_006012	OG7
TcYC6_0043300 ⚠ beta-adaptin 1, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004597	OG7
TcYC6_0059460 ⚠ pseudouridylate synthase I, putative	—	OG7 TCSYLVIO_003107 ↔ TCSYLVIO_004376	OG7

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