TcYC6_0112560

hypothetical protein, conserved
Trypanosoma cruzi Y C6 OG6: OG6_101974 OG7: OG7_0002342 133 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 133 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0011370 ⚠
heat shock protein 70
— OG7
TcYC6_0115110 ⚠
pyruvate kinase 2, putative
— OG7
TcYC6_0031370 ⚠
5'-AMP-activated protein kinase subunit beta,
— OG7
TcYC6_0113710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016660 ⚠
conserved protein, unknown function
— OG7
TcYC6_0009310 ⚠
Ubiquitin family, putative
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0124680 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0056900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0018650 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0042410 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0072050 ⚠
Tcc1i14-2.10
— OG7
TcYC6_0023240 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcYC6_0071910 ⚠
isopentenyl-diphosphate delta-isomerase (type
— OG7
TcYC6_0074310 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0080770 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0089910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0018460 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0080250 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0097340 ⚠
SET domain containing protein, putative
— OG7
TcYC6_0123410 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0005860 ⚠
vacuolar protein sorting-associated protein-l
— OG7
TcYC6_0048300 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcYC6_0006410 ⚠
vacuolar protein sorting-associated protein-l
— OG7
TcYC6_0126040 ⚠
Ribosomal protein S5, C-terminal domain conta
— OG7
TcYC6_0034830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0042140 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115840 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
TcYC6_0082160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0059600 ⚠
RNA pseudouridylate synthase, putative
— OG7
TcYC6_0024720 ⚠
putative RNA pseudouridylate synthase protein
— OG7
TcYC6_0068520 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcYC6_0051320 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0123530 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0067370 ⚠
hypothetical protein
— OG7
TcYC6_0106440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053230 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcYC6_0091260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0005360 ⚠
amidohydrolase, putative
— OG7
TcYC6_0016790 ⚠
cyclophilin 15, putative
— OG7
TcYC6_0005350 ⚠
aminoacylase, putative
— OG7
TcYC6_0005340 ⚠
amidohydrolase, putative
— OG7
TcYC6_0098750 ⚠
calmodulin, putative
— OG7
TcYC6_0051880 ⚠
phosphatidylinositol kinase, putative
— OG7
TcYC6_0081240 ⚠
Mitochondrial small ribosomal subunit Rsm22,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.