TcYC6_0011370

heat shock protein 70
Trypanosoma cruzi Y C6 OG6: OG6_100083 OG7: OG7_0000777 71 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 71 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0116640
hypothetical protein, conserved
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0123410 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0080250 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0049550
hypothetical protein, conserved
— OG7
TcYC6_0115710
hypothetical protein, conserved
— OG7
TcYC6_0018460 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0021740
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0062940
hypothetical protein, conserved
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcYC6_0115230 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
TcYC6_0120160
putative COP9 signalosome complex subunit 2
— OG7
TcYC6_0007440
ATP synthase, putative
— OG7
TcYC6_0080770 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0083670
tubulin folding cofactor D, putative
— OG7
TcYC6_0011990
Vacuolar proton pump subunit B, putative
— OG7
TcYC6_0043840
hypothetical protein, conserved
— OG7
TcYC6_0096230
hypothetical protein, conserved
— OG7
TcYC6_0098570
hypothetical protein, conserved
— OG7
TcYC6_0113520 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcYC6_0108150
Hsc70-interacting protein, putative
— OG7
TcYC6_0034830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0106500
hypothetical protein, conserved
— OG7
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0102190
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0072130 ⚠
hypothetical protein
— OG7
TcYC6_0116560
prolyl-tRNA synthetase, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0048300 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcYC6_0047190
hypothetical protein, conserved
— OG7
TcYC6_0071270 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcYC6_0123270
branch point binding protein, putative
— OG7
TcYC6_0093170
guide RNA associated protein, GAP2, putative
— OG7
TcYC6_0028460
proliferative cell nuclear antigen (PCNA), pu
— OG7
TcYC6_0096770 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
TcYC6_0098250 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0029360 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0048020
Probable N6-adenine methyltransferase, putati
— OG7
TcYC6_0047150 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0112560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0045030 ⚠
NGG1 interacting factor 3, putative
— OG7
TcYC6_0098230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0127290 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0098890
S-adenosylmethionine synthetase, putative
— OG7
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.