TcYC6_0115230

zinc-finger of a C2HC-type/Double zinc ribbon, putative
Trypanosoma cruzi Y C6 OG6: OG6_105791 OG7: OG7_0005202 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0123380 ⚠
hypothetical protein, conserved
— Both
TcYC6_0072050 ⚠
Tcc1i14-2.10
— OG7
TcYC6_0018650 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— Both
TcYC6_0102190 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
TcYC6_0023910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0018460 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0093170 ⚠
guide RNA associated protein, GAP2, putative
— Both
TcYC6_0084300 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
TcYC6_0096230 ⚠
hypothetical protein, conserved
— Both
TcYC6_0106500 ⚠
hypothetical protein, conserved
— Both
TcYC6_0093110 ⚠
hypothetical protein
— Both
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0090930 ⚠
V-type ATPase, A subunit, putative
— Both
TcYC6_0043840 ⚠
hypothetical protein, conserved
— Both
TcYC6_0123410 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0048300 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcYC6_0034830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0034960 ⚠
Eukaryotic translation initiation factor 4 ga
— OG7
TcYC6_0006040 ⚠
eukaryotic translation initiation factor 4 ga
— OG7
TcYC6_0055900 ⚠
eukaryotic translation initiation factor 4 ga
— OG7
TcYC6_0056900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0096590 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcYC6_0059460 ⚠
pseudouridylate synthase I, putative
— OG7
TcYC6_0113520 ⚠
tRNA pseudouridine synthase A-like protein, p
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0080770 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcYC6_0011370 ⚠
heat shock protein 70
— OG7
TcYC6_0026330 ⚠
calpain-like cysteine peptidase
— OG6
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— Both
TcYC6_0098570 ⚠
hypothetical protein, conserved
— Both
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— Both
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcYC6_0017070 ⚠
putative calpain-like cysteine peptidase
— OG6
TcYC6_0021670 ⚠
ATP synthase, putative
— Both
TcYC6_0021990 ⚠
protein kinase PK4, putative
— Both
TcYC6_0107880 ⚠
Facilitates chromatin transcription complex s
— Both
TcYC6_0024850 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0007440 ⚠
ATP synthase, putative
— Both
TcYC6_0120160 ⚠
putative COP9 signalosome complex subunit 2
— Both
TcYC6_0062940 ⚠
hypothetical protein, conserved
— Both
TcYC6_0116640 ⚠
hypothetical protein, conserved
— Both
TcYC6_0115710 ⚠
hypothetical protein, conserved
— Both
TcYC6_0047480 ⚠
NADH-dependent fumarate reductase
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.