TcYC6_0123410

CMGC/DYRK protein kinase, putative
Trypanosoma cruzi Y C6 OG6: OG6_150779 OG7: OG7_0001715 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0107880 ⚠
Facilitates chromatin transcription complex s
— OG7
TcYC6_0047190 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0062940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0007440 ⚠
ATP synthase, putative
— OG7
TcYC6_0093170 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcYC6_0084300 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcYC6_0047480 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— OG7
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0011370 ⚠
heat shock protein 70
— OG7
TcYC6_0043840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116640 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0021670 ⚠
ATP synthase, putative
— OG7
TcYC6_0018250 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016270 ⚠
leucine-rich repeat-containing protein
— OG7
TcYC6_0080770 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcYC6_0080240 ⚠
putative TPR-repeat-containing chaperone prot
— OG7
TcYC6_0079980 ⚠
TPR-repeat-containing chaperone protein DNAJ,
— OG7
TcYC6_0089510 ⚠
TPR-repeat protein, putative
— OG7
TcYC6_0027160 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0108150 ⚠
Hsc70-interacting protein, putative
— OG7
TcYC6_0098570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0090930 ⚠
V-type ATPase, A subunit, putative
— OG7
TcYC6_0123270 ⚠
branch point binding protein, putative
— OG7
TcYC6_0040200 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040190 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0116560 ⚠
prolyl-tRNA synthetase, putative
— OG7
TcYC6_0011990 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— OG7
TcYC6_0106500 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072130 ⚠
hypothetical protein
— OG7
TcYC6_0074310 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0093110 ⚠
hypothetical protein
— OG7
TcYC6_0115230 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
TcYC6_0080250 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0021740 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
TcYC6_0123380 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0096230 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0115710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0056900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0086600 ⚠
hypothetical protein
— OG7
TcYC6_0102190 ⚠
N(2), N(2)-dimethylguanosine tRNA methyltrans
— OG7
TcYC6_0021550 ⚠
hypothetical protein
— OG7
TcYC6_0042410 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0047680 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.