TcYC6_0080770

leucine carboxyl methyltransferase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100931 OG7: OG7_0005126 89 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 89 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0124680 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0013090 ⚠
oxidoreductase-like protein, putative
— OG7
TcYC6_0056900 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0080710 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— OG7
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcYC6_0093170 ⚠
guide RNA associated protein, GAP2, putative
— OG7
TcYC6_0030440 ⚠
hypothetical protein
— OG7
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0123860 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0069480 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
TcYC6_0122950 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047190 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0081220 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0080720 ⚠
PUB domain containing protein, putative
— OG7
TcYC6_0012460 ⚠
leucine rich repeat
— OG7
TcYC6_0015620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122820 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0108150 ⚠
Hsc70-interacting protein, putative
— OG7
TcYC6_0034830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— OG7
TcYC6_0116560 ⚠
prolyl-tRNA synthetase, putative
— OG7
TcYC6_0048300 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcYC6_0021740 ⚠
2-oxoisovalerate dehydrogenase alpha subunit,
— OG7
TcYC6_0123410 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcYC6_0080250 ⚠
zinc-finger of a C2HC-type, putative
— OG7
TcYC6_0041650 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106520 ⚠
Cold-shock DNA-binding domain containing prot
— OG7
TcYC6_0014160 ⚠
mitochondrial RNA binding protein 16
— OG7
TcYC6_0114880 ⚠
Hsp70 protein, putative
— OG7
TcYC6_0011620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106500 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— OG7
TcYC6_0007630 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0011990 ⚠
Vacuolar proton pump subunit B, putative
— OG7
TcYC6_0123270 ⚠
branch point binding protein, putative
— OG7
TcYC6_0084300 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
TcYC6_0098570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0090930 ⚠
V-type ATPase, A subunit, putative
— OG7
TcYC6_0082210 ⚠
RNA-binding protein 38, putative
— OG7
TcYC6_0103230 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0046330 ⚠
glutamine synthetase, putative
— OG7
TcYC6_0128180 ⚠
glutamine synthetase, putative
— OG7
TcYC6_0062940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0011370 ⚠
heat shock protein 70
— OG7
TcYC6_0096230 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0059460 ⚠
pseudouridylate synthase I, putative
— OG7
TcYC6_0096590 ⚠
pseudouridine synthase A-like protein, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.