TcYC6_0083670

tubulin folding cofactor D, putative
Trypanosoma cruzi Y C6 OG6: OG6_102599 OG7: OG7_0006853 199 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 199 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0031230 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0121920 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcYC6_0061240 ⚠
hypothetical protein, conserved
— Both
TcYC6_0061260 ⚠
helicase, putative
— Both
TcYC6_0061280 ⚠
helicase, putative
— Both
TcYC6_0061220 ⚠
helicase, putative
— Both
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0091190 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
TcYC6_0017360 ⚠
putative developmentally regulated phosphopro
— Both
TcYC6_0068420 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— Both
TcYC6_0095370
hypothetical protein, conserved
— Both
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
TcYC6_0065870
hypothetical protein, conserved
— Both
TcYC6_0072920
phenylalanyl-tRNA synthetase (beta subunit),
— Both
TcYC6_0080930 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
TcYC6_0116560
prolyl-tRNA synthetase, putative
— +2 more Both
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TcYC6_0086990
hypothetical protein
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcYC6_0005570 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053860 ⚠
Outer row dynein-assembly protein 7
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0069360 ⚠
replication factor C, subunit 3, putative
— OG7
TcYC6_0121490 ⚠
replication factor C subunit 3, putative
— OG7
TcYC6_0007320 ⚠
replication factor C, subunit 4, putative
— OG7
TcYC6_0048180 ⚠
ATPase family associated with various cellula
— OG7
TcYC6_0097650 ⚠
replication factor C, subunit 2, putative
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0096230
hypothetical protein, conserved
— Both
TcYC6_0098570
hypothetical protein, conserved
— Both
TcYC6_0085910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0047190
hypothetical protein, conserved
— Both
TcYC6_0111530 ⚠
6-phosphofructo-2-kinase 1
— Both
TcYC6_0034770
ribonucleoprotein p18, mitochondrial precurso
— Both
TcYC6_0046920
vacuolar ATP synthase subunit d
— Both
TcYC6_0053470
phenylalanyl-tRNA synthetase alpha chain, put
— Both
TcYC6_0091400
GRIP domain containing protein, putative
— Both
TcYC6_0026340 ⚠
hypothetical protein
— OG6
TcYC6_0017040 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcYC6_0031670
pteridine reductase
— Both
TcYC6_0072130 ⚠
hypothetical protein
— Both
TcYC6_0100340 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcYC6_0114860
Histone chaperone Rttp106-like, putative
— Both
TcYC6_0022120
ATP synthase F1 subunit gamma protein, putati
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.