TcYC6_0097650

replication factor C, subunit 2, putative
Trypanosoma cruzi Y C6 OG6: OG6_101335 OG7: OG7_0001167 128 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 128 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0101260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0056420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0069310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119340 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcYC6_0085400 ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
TcYC6_0097780 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095660 ⚠
co-chaperone GrpE, putative
— OG7
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0070930 ⚠
small nuclear ribonucleoprotein Sm-F, putativ
— OG7
TcYC6_0067890 ⚠
chaperone DNAJ protein
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0071320 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053250 ⚠
small nuclear ribonucleoprotein Sm-G, putativ
— OG7
TcYC6_0110900 ⚠
protein kinase, putative
— OG7
TcYC6_0044960 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TcYC6_0089220 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TcYC6_0044930 ⚠
hypothetical protein
— OG7
TcYC6_0044420 ⚠
putative protein kinase
— OG7
TcYC6_0044950 ⚠
hypothetical protein
— OG7
TcYC6_0044940 ⚠
hypothetical protein
— OG7
TcYC6_0066100 ⚠
ubiquitin-activating enzyme
— OG7
TcYC6_0084200 ⚠
ubiquitin activating enzyme, putative
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0065610 ⚠
hypothetical protein
— OG7
TcYC6_0004920 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcYC6_0012030 ⚠
hypothetical protein
— OG7
TcYC6_0060680 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0023240 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcYC6_0034510 ⚠
ecotin, putative
— OG7
TcYC6_0113830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0031580 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0031290 ⚠
putative 5'-3' exoribonuclease C
— OG7
TcYC6_0040110 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0061220 ⚠
helicase, putative
— OG7
TcYC6_0061280 ⚠
helicase, putative
— OG7
TcYC6_0061260 ⚠
helicase, putative
— OG7
TcYC6_0061240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0045770 ⚠
hypothetical protein
— OG7
TcYC6_0045680 ⚠
TLD, putative
— OG7
TcYC6_0126250 ⚠
PIF1 helicase-like protein
— OG7
TcYC6_0016700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0065870 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043350 ⚠
zinc finger ccch and cchc domain-containing p
— OG7
TcYC6_0115710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043360 ⚠
PUB domain containing protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.