TcYC6_0089220

eukaryotic translation initiation factor 2-alpha kinase 2
Trypanosoma cruzi Y C6 OG6: OG6_107794 OG7: OG7_0002967 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0069480 ⚠
Putative death-receptor fusion protein (DUF24
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0102590 ⚠
RNA-binding protein RBP10, putative
— OG7
TcYC6_0113830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0056420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0097780 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0016880 ⚠
MORN repeat-containing protein
— OG7
TcYC6_0067890 ⚠
chaperone DNAJ protein
— OG7
TcYC6_0065610 ⚠
hypothetical protein
— OG7
TcYC6_0004920 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcYC6_0040640 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0090430 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
TcYC6_0084460 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
TcYC6_0084550 ⚠
kinetoplastid kinetochore protein 18
— OG7
TcYC6_0048180 ⚠
ATPase family associated with various cellula
— OG7
TcYC6_0122820 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0118040 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
TcYC6_0106170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0026700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0109730 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0014800 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0097650 ⚠
replication factor C, subunit 2, putative
— OG7
TcYC6_0068150 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0007320 ⚠
replication factor C, subunit 4, putative
— OG7
TcYC6_0097460 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121490 ⚠
replication factor C subunit 3, putative
— OG7
TcYC6_0081900 ⚠
putative replication factor C, subunit 1
— OG7
TcYC6_0069360 ⚠
replication factor C, subunit 3, putative
— OG7
TcYC6_0016700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122950 ⚠
hypothetical protein, conserved
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.