TcYC6_0109730

hypothetical protein, conserved
Trypanosoma cruzi Y C6 OG6: OG6_146709 OG7: OG7_0043725 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0118040 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0089220 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TcYC6_0016870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcYC6_0069360 ⚠
replication factor C, subunit 3, putative
— OG7
TcYC6_0081900 ⚠
putative replication factor C, subunit 1
— OG7
TcYC6_0121490 ⚠
replication factor C subunit 3, putative
— OG7
TcYC6_0007320 ⚠
replication factor C, subunit 4, putative
— OG7
TcYC6_0048180 ⚠
ATPase family associated with various cellula
— OG7
TcYC6_0097650 ⚠
replication factor C, subunit 2, putative
— OG7
TcYC6_0044220 ⚠
proteasome alpha 7 subunit, putative
— Both
TcYC6_0102590 ⚠
RNA-binding protein RBP10, putative
— Both
TcYC6_0103040 ⚠
T-complex protein 1, zeta subunit, putative
— OG7
TcYC6_0084460 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TcYC6_0004920 ⚠
Beta-lactamase superfamily domain containing
— Both
TcYC6_0065610 ⚠
hypothetical protein
— Both
TcYC6_0044600
proteasome beta 3 subunit, putative
— Both
TcYC6_0068330
helicase, putative
— OG6
TcYC6_0028290 ⚠
ubiquitin hydrolase
— Both
TcYC6_0084550
kinetoplastid kinetochore protein 18
— Both
TcYC6_0016700
hypothetical protein, conserved
— Both
TcYC6_0103930
acetyl-CoA carboxylase
— Both
TcYC6_0098360
eukaryotic translation initiation factor 3 su
— Both
TcYC6_0113830
hypothetical protein, conserved
— Both
TcYC6_0125830 ⚠
proteasome subunit beta type-5, putative
— OG7
TcYC6_0014800
hypothetical protein, conserved
— OG7
TcYC6_0090430 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
TcYC6_0114250
RNA-binding protein, putative
— OG7
TcYC6_0065750 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
TcYC6_0099660 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0014480 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
TcYC6_0062920 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
TcYC6_0066250 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
TcYC6_0114670 ⚠
ATP-dependent RNA helicase HEL67
— OG7
TcYC6_0126490 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
TcYC6_0049920 ⚠
exosome-associated protein 2, putative
— Both
TcYC6_0053590 ⚠
cyclin 9, putative
— OG7
TcYC6_0026700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0106170 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068150
hypothetical protein, conserved
— OG7
TcYC6_0117350 ⚠
proteasome alpha 7 subunit, putative
— OG7
TcYC6_0019050 ⚠
proteasome alpha 3 subunit, putative
— OG7
TcYC6_0125780 ⚠
proteasome subunit alpha type-1, putative
— OG7
TcYC6_0022090 ⚠
proteasome subunit alpha type-5, putative
— OG7
TcYC6_0121250 ⚠
T-complex protein 1, theta subunit, putative
— OG7
TcYC6_0073570 ⚠
T-complex protein 1, beta subunit, putative
— OG7
TcYC6_0070070 ⚠
T-complex protein 1, eta subunit, putative
— OG7
TcYC6_0097780
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.