TcYC6_0127520

ATP-dependent RNA helicase MTR4
Trypanosoma cruzi Y C6 OG6: OG6_100340 OG7: OG7_0002665 144 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 144 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0061280 ⚠
helicase, putative
— OG7
TcYC6_0007320 ⚠
replication factor C, subunit 4, putative
— OG7
TcYC6_0023240 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcYC6_0061240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0040710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0025640 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— OG7
TcYC6_0100560 ⚠
Domain of unknown function (DUF3437), putativ
— OG7
TcYC6_0121490 ⚠
replication factor C subunit 3, putative
— OG7
TcYC6_0081900 ⚠
putative replication factor C, subunit 1
— OG7
TcYC6_0069360 ⚠
replication factor C, subunit 3, putative
— OG7
TcYC6_0072660 ⚠
hypothetical protein
— OG7
TcYC6_0056290 ⚠
protein farnesyltransferase, putative
— OG7
TcYC6_0031580 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0104860 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0012520 ⚠
p21-C-terminal region-binding protein, putati
— OG7
TcYC6_0107490 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0065870 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0073050 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
TcYC6_0086990 ⚠
hypothetical protein
— OG7
TcYC6_0043350 ⚠
zinc finger ccch and cchc domain-containing p
— OG7
TcYC6_0040110 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0095240 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
TcYC6_0011810 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcYC6_0014560 ⚠
geranylgeranyltransferase type I beta subunit
— OG7
TcYC6_0012030 ⚠
hypothetical protein
— OG7
TcYC6_0104830 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0061260 ⚠
helicase, putative
— OG7
TcYC6_0077260 ⚠
translation initiation factor IF-2, putative
— OG7
TcYC6_0083670 ⚠
tubulin folding cofactor D, putative
— OG7
TcYC6_0125510 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0104800 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0101260 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089960 ⚠
Carboxypeptidase-like protein
— OG7
TcYC6_0043810 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TcYC6_0124390 ⚠
putative metallo-peptidase, Clan MC, Family M
— OG7
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
TcYC6_0071320 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0107860 ⚠
nuclear transcription factor, putative
— OG7
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— OG7
TcYC6_0112960 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044190 ⚠
Phosphoenolpyruvate carboxykinase, related
— OG7
TcYC6_0076090 ⚠
Phosducin, putative
— OG7
TcYC6_0050570 ⚠
ATP binding protein-like protein, putative
— OG7
TcYC6_0045770 ⚠
hypothetical protein
— OG7
TcYC6_0044600 ⚠
proteasome beta 3 subunit, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.