TcYC6_0025640

inosine-5'-monophosphate dehydrogenase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100534 OG7: OG7_0002926 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0047150 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcYC6_0074290 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0116260 ⚠
putative 5-oxoprolinase
— Both
TcYC6_0043390 ⚠
hypothetical protein, conserved
— Both
TcYC6_0043860 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
TcYC6_0098250 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcYC6_0110090 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcYC6_0029360 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcYC6_0046450 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— Both
TcYC6_0104890 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
TcYC6_0047370 ⚠
KRI1-like family/KRI1-like family C-terminal,
— OG6
TcYC6_0040200 ⚠
hypothetical protein, conserved
— Both
TcYC6_0098230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcYC6_0127290 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcYC6_0062240 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0055620 ⚠
EMG1/NEP1 methyltransferase, putative
— OG6
TcYC6_0067600 ⚠
rRNA processing protein, putative
— OG6
TcYC6_0117910 ⚠
ATP synthase subunit beta, mitochondrial
— Both
TcYC6_0098240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TcYC6_0066520 ⚠
glutamine hydrolysing (not ammonia-dependent)
— Both
TcYC6_0095440 ⚠
ribosome biogenesis regulatory protein (RRS1)
— OG6
TcYC6_0095250 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0127520 ⚠
ATP-dependent RNA helicase MTR4
— OG7
TcYC6_0071270 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcYC6_0104900 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
TcYC6_0040190 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072780 ⚠
aminopeptidase, putative,metallo-peptidase, C
— OG7
TcYC6_0107860 ⚠
nuclear transcription factor, putative
— OG7
TcYC6_0023910 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0107480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0022580 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0126720 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— Both
TcYC6_0104800 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0104830 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0014560 ⚠
geranylgeranyltransferase type I beta subunit
— OG7
TcYC6_0086990 ⚠
hypothetical protein
— OG7
TcYC6_0077600 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0015370 ⚠
aspartyl-tRNA synthetase, putative
— OG7
TcYC6_0104860 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0068840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0091340 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcYC6_0016320 ⚠
ARM-like helical domain-containing protein
— OG6
TcYC6_0067770 ⚠
Casein kinase II
— OG6
TcYC6_0089430 ⚠
asparaginyl-tRNA synthetase, putative
— Both
TcYC6_0069310 ⚠
hypothetical protein, conserved
— Both
TcYC6_0095370 ⚠
hypothetical protein, conserved
— Both
TcYC6_0110770 ⚠
aspartyl aminopeptidase, putative
— Both
TcYC6_0031370 ⚠
5'-AMP-activated protein kinase subunit beta,
— Both
TcYC6_0125510 ⚠
hypothetical protein, conserved
— Both
TcYC6_0077260 ⚠
translation initiation factor IF-2, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.