TcYC6_0098230

glyceraldehyde 3-phosphate dehydrogenase, putative
Trypanosoma cruzi Y C6 OG6: OG6_100218 OG7: OG7_0002325 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0060380 ⚠
glutamic--pyruvic transaminase, putative
— Both
TcYC6_0050280 ⚠
hypothetical protein
— OG7
TcYC6_0126920 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
TcYC6_0106520 ⚠
Cold-shock DNA-binding domain containing prot
— OG7
TcYC6_0012710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0060470 ⚠
glucose-6-phosphate isomerase, glycosomal, pu
— Both
TcYC6_0112960 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcYC6_0048370 ⚠
GMP reductase
— OG6
TcYC6_0025640 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— Both
TcYC6_0115110 ⚠
pyruvate kinase 2, putative
— Both
TcYC6_0075920 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0060390 ⚠
glutamic--pyruvic transaminase, putative
— Both
TcYC6_0014160 ⚠
mitochondrial RNA binding protein 16
— Both
TcYC6_0125810 ⚠
universal minicircle sequence binding protein
— Both
TcYC6_0125800 ⚠
poly-zinc finger protein 2, putative
— OG6
TcYC6_0125820 ⚠
universal minicircle sequence binding protein
— Both
TcYC6_0052930 ⚠
G5-interacting protein, putative
— Both
TcYC6_0028100 ⚠
tryparedoxin peroxidase, putative
— Both
TcYC6_0084380 ⚠
fatty acyl CoA synthetase 2, putative
— Both
TcYC6_0044350 ⚠
NGG1 interacting factor 3, putative
— OG7
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0113650 ⚠
GDP-mannose 4,6 dehydratase
— OG7
TcYC6_0028460 ⚠
proliferative cell nuclear antigen (PCNA), pu
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0074470 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0110270 ⚠
protein farnesyltransferase alpha subunit, pu
— OG7
TcYC6_0045030 ⚠
NGG1 interacting factor 3, putative
— OG7
TcYC6_0128180 ⚠
glutamine synthetase, putative
— Both
TcYC6_0074210 ⚠
isovaleryl-coA dehydrogenase, putative
— OG7
TcYC6_0011370 ⚠
heat shock protein 70
— OG7
TcYC6_0007840 ⚠
aldehyde dehydrogenase, putative
— OG7
TcYC6_0098600 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcYC6_0096770 ⚠
queuine tRNA-ribosyltransferase, putative
— OG7
TcYC6_0066340 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0032550 ⚠
GAF domain/TIP41-like family, putative
— OG7
TcYC6_0076500 ⚠
GTP-binding protein, putative
— OG7
TcYC6_0074800 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TcYC6_0081230 ⚠
fumarate hydratase, putative
— Both
TcYC6_0098890 ⚠
S-adenosylmethionine synthetase, putative
— Both
TcYC6_0032470 ⚠
peroxidoxin
— Both
TcYC6_0028640 ⚠
putative glutamate dehydrogenase
— Both
TcYC6_0025510 ⚠
fructose-1,6-bisphosphatase, cytosolic, putat
— Both
TcYC6_0102650 ⚠
adenylosuccinate synthetase, putative
— Both
TcYC6_0110280 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcYC6_0098160 ⚠
aldehyde dehydrogenase, putative
— Both
TcYC6_0028760 ⚠
hypothetical protein, conserved
— Both
TcYC6_0064490 ⚠
hypothetical protein, conserved
— Both
TcYC6_0028130 ⚠
tryparedoxin peroxidase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.