TcYC6_0075920

GTP-binding protein, putative
Trypanosoma cruzi Y C6 OG6: OG6_100571 OG7: OG7_0003363 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0009260 ⚠
hypothetical protein, conserved
— Both
TcYC6_0004930 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0012710 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0113650 ⚠
GDP-mannose 4,6 dehydratase
— OG7
TcYC6_0065620 ⚠
hypothetical protein
— OG7
TcYC6_0126720 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0076180 ⚠
esterase, putative
— Both
TcYC6_0076050 ⚠
esterase, putative
— Both
TcYC6_0098240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0050860 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0050990 ⚠
superoxide dismutase, putative
— Both
TcYC6_0061710 ⚠
PITH domain-containing protein
— Both
TcYC6_0087910 ⚠
hypothetical protein, conserved
— Both
TcYC6_0128180 ⚠
glutamine synthetase, putative
— Both
TcYC6_0044570 ⚠
hypothetical protein, conserved
— Both
TcYC6_0053220 ⚠
exportin 1, putative
— Both
TcYC6_0094070 ⚠
dephospho-CoA kinase, putative
— OG6
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— OG7
TcYC6_0072350 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
TcYC6_0065630 ⚠
hypothetical protein
— OG7
TcYC6_0098250 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0029360 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0065640 ⚠
hypothetical protein
— OG7
TcYC6_0007260 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0052370 ⚠
iron superoxide dismutase, putative
— Both
TcYC6_0051940 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0047150 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0071270 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TcYC6_0098230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0127290 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0070700 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0085450 ⚠
monothiol glutaredoxin, putative
— OG7
TcYC6_0113860 ⚠
CYTH domain containing protein, putative
— Both
TcYC6_0032520 ⚠
GDP-mannose pyrophosphorylase
— Both
TcYC6_0055760 ⚠
hypothetical protein, conserved
— Both
TcYC6_0049100 ⚠
Macro domain containing protein, putative
— Both
TcYC6_0063760
mitogen-activated protein kinase 3, putative
— OG6
TcYC6_0064790 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0062220 ⚠
thioredoxin-like protein, putative
— Both
TcYC6_0125230 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
TcYC6_0058160 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TcYC6_0097630 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcYC6_0074750 ⚠
hypothetical protein, conserved
— Both
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— Both
TcYC6_0004940 ⚠
mitochondrial DNA polymerase beta, putative
— Both
TcYC6_0098780 ⚠
hypothetical protein, conserved
— Both
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.