TcYC6_0113530

WD domain, G-beta repeat, putative
Trypanosoma cruzi Y C6 OG6: OG6_146807 OG7: OG7_0007715 122 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 122 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0075920 ⚠
GTP-binding protein, putative
— Both
TcYC6_0128180 ⚠
glutamine synthetase, putative
— Both
TcYC6_0046330 ⚠
glutamine synthetase, putative
— Both
TcYC6_0045470
hypothetical protein, conserved
— Both
TcYC6_0091370 ⚠
ubiquitin hydrolase, putative
— Both
TcYC6_0018570
tc40 antigen-like, putative
— Both
TcYC6_0061720 ⚠
translation initiation factor EIF-2b alpha su
— Both
TcYC6_0060410 ⚠
cyclosome/APC complex protein, putative
— Both
TcYC6_0040230
AAA ATPase, putative
— Both
TcYC6_0111330 ⚠
radial spoke protein RSP10, putative
— Both
TcYC6_0012710
hypothetical protein, conserved
— Both
TcYC6_0087910
hypothetical protein, conserved
— Both
TcYC6_0064370 ⚠
translation initiation factor 2b, delta subun
— OG7
TcYC6_0073890 ⚠
translation initiation factor eIF2B subunit-l
— OG7
TcYC6_0042540 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089660 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0124120 ⚠
Anaphase-promoting complex, cyclosome, subuni
— OG7
TcYC6_0050280 ⚠
hypothetical protein
— OG7
TcYC6_0048030
Kinetochore interacting protein 5
— OG7
TcYC6_0115610 ⚠
tubulin-specific chaperone, putative
— OG7
TcYC6_0065620 ⚠
hypothetical protein
— OG7
TcYC6_0004930 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
TcYC6_0065640 ⚠
hypothetical protein
— OG7
TcYC6_0065630 ⚠
hypothetical protein
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0055850 ⚠
Component of motile flagella 6
— OG7
TcYC6_0043480
hypothetical protein, conserved
— OG7
TcYC6_0098250 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0029360 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0047150 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0098230 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0127290 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0098240 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— OG7
TcYC6_0126720 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0016180
dynein heavy chain, putative
— OG7
TcYC6_0095280
hypothetical protein, conserved
— OG7
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0109490
hypothetical protein, conserved
— OG7
TcYC6_0103200
hypothetical protein
— OG7
TcYC6_0028290 ⚠
ubiquitin hydrolase
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0067760 ⚠
ubiquitin hydrolase
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.