TcYC6_0089660

Guanine nucleotide exchange factor in Golgi transport N-terminal/Sec7 domain
Trypanosoma cruzi Y C6 OG6: OG6_154458 OG7: OG7_0001170 155 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 155 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0067840 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0061720 ⚠
translation initiation factor EIF-2b alpha su
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0087400 ⚠
25 kDa translation elongation factor 1-beta,
— OG7
TcYC6_0125890 ⚠
neurobeachin/beige protein
— OG7
TcYC6_0095490 ⚠
pdz domain containing protein, putative
— OG7
TcYC6_0066360 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcYC6_0060410 ⚠
cyclosome/APC complex protein, putative
— OG7
TcYC6_0019460 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0114770 ⚠
putative intraflagellar transport protein 140
— OG7
TcYC6_0091620 ⚠
putative beta prime cop protein
— OG7
TcYC6_0103200 ⚠
hypothetical protein
— OG7
TcYC6_0109490 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0048030 ⚠
Kinetochore interacting protein 5
— OG7
TcYC6_0060680 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0048900 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcYC6_0022010 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0030670 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095280 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0079740 ⚠
intraflagellar transport protein 122, putativ
— OG7
TcYC6_0009190 ⚠
Tetratricopeptide repeat, putative
— OG7
TcYC6_0028200 ⚠
putative inositol/phosphatidylinositol phosph
— OG7
TcYC6_0064470 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0127460 ⚠
fibrillarin, putative
— OG7
TcYC6_0109010 ⚠
Present in the outer mitochondrial membrane p
— OG7
TcYC6_0052760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0121120 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcYC6_0097230 ⚠
endosomal trafficking protein RME-8, putative
— OG7
TcYC6_0043310 ⚠
HIT zinc finger, putative
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0016180 ⚠
dynein heavy chain, putative
— OG7
TcYC6_0077310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0076120 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0070750 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcYC6_0092980 ⚠
Tripartite attachment complex protein 102
— OG7
TcYC6_0075070 ⚠
hypothetical protein
— OG7
TcYC6_0016780 ⚠
transmembrane protein, conserved
— OG7
TcYC6_0087430 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0077130 ⚠
dynein intermediate chain, putative
— OG7
TcYC6_0063680 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— OG7
TcYC6_0081180 ⚠
Dynein intermediate chain 1, axonemal
— OG7
TcYC6_0107960 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0018420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0086600 ⚠
hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.