TcYC6_0016180

dynein heavy chain, putative
Trypanosoma cruzi Y C6 OG6: OG6_100908 OG7: OG7_0004933 149 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 149 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0079240 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
TcYC6_0081750 ⚠
dynein light chain p28, axonemal, putative
— OG7
TcYC6_0058600 ⚠
putative dynein arm light chain
— OG7
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0055300 ⚠
WW domain containing protein, putative
— OG7
TcYC6_0092100 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121960 ⚠
ubiquitin-protein ligase, putative
— OG7
TcYC6_0114770
putative intraflagellar transport protein 140
— OG7
TcYC6_0075070 ⚠
hypothetical protein
— OG7
TcYC6_0119810 ⚠
translation elongation factor EF-2, putative
— OG7
TcYC6_0080620 ⚠
elongation factor 2
— OG7
TcYC6_0078090 ⚠
serine peptidase , putative
— OG7
TcYC6_0080640 ⚠
elongation factor 2
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0000830 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
TcYC6_0080670 ⚠
elongation factor 2
— OG7
TcYC6_0080610 ⚠
elongation factor 2
— OG7
TcYC6_0080660 ⚠
elongation factor 2
— OG7
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— OG7
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— OG7
TcYC6_0048910 ⚠
5'-3' exoribonuclease B, putative
— OG7
TcYC6_0114430 ⚠
fibrillarin, putative
— OG7
TcYC6_0127460 ⚠
fibrillarin, putative
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0021660 ⚠
structural maintenance of chromosome protein
— OG7
TcYC6_0066360 ⚠
structural maintenance of chromosome 3 protei
— OG7
TcYC6_0073980
intraflagellar transport protein 88
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0089970 ⚠
regulatory subunit of protein kinase a-like p
— OG7
TcYC6_0113530
WD domain, G-beta repeat, putative
— OG7
TcYC6_0052520
coatomer subunit epsilon
— OG7
TcYC6_0043480
hypothetical protein, conserved
— OG7
TcYC6_0095280
hypothetical protein, conserved
— OG7
TcYC6_0083620
Nucleoporin NUP76
— OG7
TcYC6_0075560 ⚠
cleavage and polyadenylation specificity fact
— OG7
TcYC6_0052760 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0009190
Tetratricopeptide repeat, putative
— OG7
TcYC6_0096930
cyclosome subunit, putative
— OG7
TcYC6_0103200
hypothetical protein
— OG7
TcYC6_0109490
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.