TcYC6_0048910

5'-3' exoribonuclease B, putative
Trypanosoma cruzi Y C6 OG6: OG6_156818 OG7: OG7_0003221 193 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 193 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0099570 ⚠
ubiquitin-protein ligase-like, putative
— OG7
TcYC6_0119740 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0111760 ⚠
quinone oxidoreductase, putative
— OG7
TcYC6_0111400 ⚠
inorganic pyrophosphatase, putative
— OG7
TcYC6_0012480 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
TcYC6_0044720 ⚠
haloacid dehalogenase hydrolase, putative
— OG7
TcYC6_0053430 ⚠
Alpha/beta hydrolase family, putative
— OG7
TcYC6_0146170 ⚠
retrotransposon hot spot (RHS) protein, putat
— OG7
TcYC6_0104220 ⚠
hypothetical protein
— OG7
TcYC6_0065780 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049760 ⚠
enoyl-CoA hydratase/isomerase family protein,
— OG7
TcYC6_0061710 ⚠
PITH domain-containing protein
— OG7
TcYC6_0051250 ⚠
terminal uridylyltransferase 4
— OG7
TcYC6_0115010 ⚠
N-myristoyl transferase, putative
— OG7
TcYC6_0106350 ⚠
diphthine synthase, putative
— OG7
TcYC6_0055760 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcYC6_0064790 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
TcYC6_0064930 ⚠
hypothetical protein
— OG7
TcYC6_0064940 ⚠
putative GMP synthase
— OG7
TcYC6_0055560 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119510 ⚠
General negative regulator of transcription s
— OG7
TcYC6_0040230 ⚠
AAA ATPase, putative
— OG7
TcYC6_0078830 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0002180 ⚠
hypothetical protein
— OG7
TcYC6_0023220 ⚠
dynein arm light chain, putative
— OG7
TcYC6_0069650 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
TcYC6_0089530 ⚠
Sec7 domain containing protein, putative
— OG7
TcYC6_0094770 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0058600 ⚠
putative dynein arm light chain
— OG7
TcYC6_0083610 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0043480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0095890 ⚠
ubiquitin-protein ligase
— OG7
TcYC6_0113530 ⚠
WD domain, G-beta repeat, putative
— OG7
TcYC6_0115610 ⚠
tubulin-specific chaperone, putative
— OG7
TcYC6_0061620 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0049440 ⚠
cyclic nucleotide-binding protein
— OG7
TcYC6_0021890 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
TcYC6_0114430 ⚠
fibrillarin, putative
— OG7
TcYC6_0113590 ⚠
putative Associated kinase of Tb14-3-3
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0124130 ⚠
structural maintenance of chromosome (SMC), p
— OG7
TcYC6_0101710 ⚠
protein kinase A regulatory subunit
— OG7
TcYC6_0126240 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0022750 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0018570 ⚠
tc40 antigen-like, putative
— OG7
TcYC6_0064370 ⚠
translation initiation factor 2b, delta subun
— OG7
TcYC6_0065620 ⚠
hypothetical protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.