TcYC6_0106350

diphthine synthase, putative
Trypanosoma cruzi Y C6 OG6: OG6_101531 OG7: OG7_0006651 147 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 147 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0107500 ⚠
Kinesin-13 4, putative
— OG7
TcYC6_0061710
PITH domain-containing protein
— Both
TcYC6_0052500 ⚠
protein phosphatase 2C
— OG6
TcYC6_0115010
N-myristoyl transferase, putative
— Both
TcYC6_0081590 ⚠
aldo/keto reductase, putative
— Both
TcYC6_0106040 ⚠
putative amino acid transporter
— OG6
TcYC6_0026760 ⚠
putative amino acid transporter
— OG6
TcYC6_0058160 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
TcYC6_0097630 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcYC6_0050820 ⚠
amino acid transporter, putative
— OG6
TcYC6_0026820 ⚠
putative amino acid transporter
— OG6
TcYC6_0026780 ⚠
putative amino acid transporter
— OG6
TcYC6_0026750 ⚠
putative amino acid transporter
— OG6
TcYC6_0026770 ⚠
putative amino acid transporter
— OG6
TcYC6_0055560
hypothetical protein, conserved
— Both
TcYC6_0092250 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0064790 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcYC6_0064930 ⚠
hypothetical protein
— Both
TcYC6_0064940 ⚠
putative GMP synthase
— Both
TcYC6_0152760 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0125960 ⚠
putative 5'-3' exoribonuclease D
— Both
TcYC6_0151050 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0013770 ⚠
putative 5'-3' exoribonuclease A
— Both
TcYC6_0152900 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0150680 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0054780
transaldolase, putative
— Both
TcYC6_0012930 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0081270 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcYC6_0012960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcYC6_0047030 ⚠
aspartate aminotransferase, putative
— Both
TcYC6_0012390
tRNA threonylcarbamoyl adenosine modification
— Both
TcYC6_0045140
Component of motile flagella 15
— Both
TcYC6_0045150
electron-transfer-flavoprotein, alpha polypep
— Both
TcYC6_0030300
alanine racemase, putative
— Both
TcYC6_0092460
SEP domain containing protein, putative
— Both
TcYC6_0077340 ⚠
transcription elongation factor-like protein,
— Both
TcYC6_0085510 ⚠
Kinesin-13 1, putative
— OG7
TcYC6_0080170 ⚠
ubiquitin-like protein, putative
— OG7
TcYC6_0112990 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0009920 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
TcYC6_0022140 ⚠
RNA polymerase II, putative
— OG7
TcYC6_0025610 ⚠
choline/carnitine O-acyltransferase , putativ
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0113040 ⚠
eukaryotic translation initiation factor 4E (
— OG7
TcYC6_0073110 ⚠
choline/carnitine O-acetyltransferase, putati
— OG7
TcYC6_0115440 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0046790 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
TcYC6_0092480 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
TcYC6_0051250 ⚠
terminal uridylyltransferase 4
— OG7
TcYC6_0084730 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.